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Cefeprime 500 MG Injection

Manufactured by: Veritaz Healthcare Ltd.
Composition: Cefipime
Prescription Required: Yes
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Description

Cefeprime 500 MG Injection is a broad spectrum antibiotic which is used to treat a variety of conditions caused by bacteria in the lungs, urinary tract, and abdomen. The intramuscular injection is used to treat urinary tract infections caused by Escherichia coli.

Side effects

Major & minor side effects for Cefeprime 500 MG Injection

  • Abdominal painsevere
  • Bleeding gumssevere
  • Convulsionssevere
  • Feversevere
  • Headachesevere
  • Yellowing of skin and eyessevere
  • Swelling of footsevere
  • Diarrheasevererare
  • Redness of skin
  • Pain at the injection site
  • Itching of vagina or genital arearare
  • Sour mouthrare
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Cefeprime 500 MG Injection

Onset of action

The peak effect of this medicine can be observed in 0.5 to 1.5 hours after an intravenous dose and 1 to 2 hours after an intramuscular dose.

Duration of effect

The effect of this medicine lasts for an average duration of 6 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

Usage while breast-feeding?

This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

Substitutes

List of substitutes for Cefeprime 500 MG Injection

Below is the list of medicines, which have the same composition, strength and form as Cefeprime 500 MG Injection, and hence can be used as its substitute.
C Pime 500 MG Injection
Emcure Pharmaceuticals Ltd.
Cepime 500 MG Injection
Alembic Ltd.
Forpar 500 MG Injection
Cipla Ltd.
Micropime 500 MG Injection
Micro Labs Ltd.
Scud 500 MG Injection
Zuventus Healthcare Ltd.

What is it prescribed for?

Uses of Cefeprime 500 MG Injection

  • Pneumonia

    Cefeprime 500 MG Injection is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

  • Pyelonephriits

    Cefeprime 500 MG Injection is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

  • Skin and Soft tissue infections

    Cefeprime 500 MG Injection is used to treat skin and soft tissue infections caused by Staphylococcus aureus and Streptococcus pyogenes.

  • Intra-abdominal Infection

    Cefeprime 500 MG Injection is used in the treatment of intra-abdominal infections caused by Helicobacter pylori, Staphylococci and Streptococci.

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When not to use?

Contraindications of Cefeprime 500 MG Injection

  • Allergy

    Avoid if you have a known allergy to Cefeprime 500 MG Injection or any other Beta-lactam antibiotics like penicillins or cephalosporins.

Dosage

  • Missed Dose

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Impaired kidney function

    severe
    The blood concentration of intravenous Cefeprime 500 MG Injection may increase in the patients suffering from impaired kidney function. Suitable dose adjustments are to be made based on the severity of the condition. Frequent monitoring of kidney function tests is necessary.

  • Colitis

    moderate
    Avoid if you experience severe diarrhea, abdominal pain, and blood in stools after taking Cefeprime 500 MG Injection. Inform the doctor if you are suffering from any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

  • Impaired liver function

    moderate
    Use with caution if you have any liver disease or a family history of liver disease. Regular liver function tests are to be performed. Inform the doctor if you have any liver disease or if you develop any undesired effect.

  • Seizure disorders

    moderate
    Use with caution if you have any seizure disorder or a family history of seizures. Appropriate dose adjustments are to be made if you are suffering from a kidney disease. Discontinue if seizure is due to Cefeprime 500 MG Injection. Start with appropriate anticonvulsant medicine if it is clinically indicated.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Make sure that the medicine is dissolved properly. Do not take if any particulate matter is visible. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of course.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

  • Breast-feeding

    - This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

General warnings

  • Allergy

    - Avoid taking this medicine if you have a known allergy to it or any other Beta-lactam antibiotics like penicillins and cephalosporins. Seek immediate medical attention if the patient experiences any allergic symptoms like rash, itching, nausea or vomiting, swelling of lips, hands, and feet.

  • Clostridium difficile-associated diarrhea

    - Avoid if you experience severe diarrhea after receiving Cefeprime 500 MG Injection. As antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine which promotes the growth of bacteria called clostridium difficile.

  • Drug-resistance

    - Usage of Cefeprime 500 MG Injection without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

  • Impaired kidney function

    - Use with caution if you have a preexisting kidney disease. Appropriate dose adjustments are to be made based of CrCl or eGFR.

  • Neurotoxicity

    - Cefeprime 500 MG Injection may increase the risk of serious adverse effects like encephalopathy, seizures, and nonconvulsive status epilepticus. These reactions may occur in the patients with impaired kidney function with no proper dose adjustment.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

Cefeprime 500 MG Injection is a broad spectrum antibiotic. It works by interfering with the bacterial cell wall synthesis.

Legal Status

Approved
Approved
Unknown
Approved

Classification

Category
Cephalosporins
Schedule
Schedule H

References

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.