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Canmab 440 Injection
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Canmab 440 Injection

Manufactured byBIOCON LTD
ContainsTrastuzumab
Description
Canmab 440 Injection is an anti-cancer medicine. It is used to treat breast and stomach cancer. It works by stopping the growth of cancer cells. Canmab 440 Injection has some side effects like diarrhoea, constipation, loss of appetite, stomach pain, heartburn, acne, headache, back pain, muscle pain, etc. Consult your doctor if they bother you for a longer time or worsen. Canmab 440 Injection should be avoided if you are allergic to it. Canmab 440 Injection is given in a hospital setting by a qualified healthcare professional. The dose and duration of treatment will be determined by your doctor based on the severity of your condition. Do not miss the dose of this injection and continue the treatment for the recommended duration for best results. Canmab 440 Injection may not be suitable for everyone. Inform your doctor if you have high blood pressure, or heart or lung problems. Also, inform your doctor about your ongoing medications to avoid undesired effects. Consult your doctor if you are pregnant or are breastfeeding before receiving this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Canmab 440 Injection

Vivitra 440 mg Injection
Zydus Cadila
Herclon Injection
Roche India
Hertraz 440 Injection
Mylan Pharmaceuticals

Side effects

Major & minor side effects for Canmab 440 Injection

  • Fever
  • Headache
  • Nausea and Vomiting
  • Tiredness and weakness
  • Shortness of breath
  • Diarrhoea
  • Reduction in blood cell count
  • Infections
  • Muscle and joint pain
  • Cough
  • Swelling of the face, lips, or tongue
  • Change in taste
  • Sleep disturbances
  • Stomach pain
  • Heartburn
  • Depression
  • Unusual bleeding or bruising
  • Pale skin
  • Constipation
  • Back pain
  • Loss of appetite

Uses of Canmab 440 Injection

What is it prescribed for?

  • Breast cancer
  • Metastatic gastric cancer
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Canmab 440 Injection to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Canmab 440 Injection remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Canmab 440 Injection.
  • Can this medicine be taken during pregnancy?
    Canmab 440 Injection is unsafe for use during pregnancy as it can harm the developing foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of safety information, Canmab 440 Injection is not recommended for use while breastfeeding and for seven months after the last dose.

Allergy

Canmab 440 Injection is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Canmab 440 Injection is unsafe for use during pregnancy as it can harm the developing foetus. Consult your doctor if you are pregnant.

Breast-feeding

Due to the lack of safety information, Canmab 440 Injection is not recommended for use while breastfeeding and for seven months after the last dose.
General warnings

Women of childbearing potential

Use of Canmab 440 Injection during pregnancy may cause harm to the developing foetus. Hence, women of childbearing potential should use effective contraceptive methods while on treatment with this medicine and for seven months after completing the treatment.

Driving or operating machines

Use of Canmab 440 Injection may cause drowsiness or dizziness in some cases. Hence, avoid performing activities such as driving vehicles and operating machines if you experience such symptoms during treatment with this medicine.

Missed Dose

As Canmab 440 Injection is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss a scheduled appointment for a dose of this medicine, contact your doctor immediately for further instructions.

Overdose

As Canmab 440 Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Leflunomide

Live vaccines

Etanercept

Doxorubicin

Ganciclovir

Adalimumab

Paclitaxel

Warfarin

Baricitinib

Disease interactions

Pulmonary toxicity

Canmab 440 Injection should be used with extreme caution as it may cause respiratory toxicity such as shortness of breath, difficulty in breathing, scarring of the lungs, excess fluid in the lungs, etc. It is not recommended for use if you have shortness of breath due to complications of advanced cancer or if you require supplementation with oxygen therapy.

Cardiovascular disease

Canmab 440 Injection should be used with caution if you have heart problems as it may further worsen your condition.

Peripheral Neuropathy

Peripheral neuropathy is the damage of nerves outside your brain and spinal cord. This may lead to sharp, throbbing, or burning pain, pricking sensation, and numbness, usually in the hands and feet. Canmab 440 Injection should be used with caution as it may cause peripheral neuropathy.

Thrombocytopenia

Thrombocytopenia is a condition of decreased platelet count in your body. Platelets are colorless blood cells that help blood clot and arrest bleeding. Canmab 440 Injectionshould be used with extreme caution as it may cause thrombocytopenia.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Canmab 440 Injection is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. The dose and frequency of administration are very specific and should not be missed. Your doctor may suggest a few laboratory tests during and after the treatment with this medicine. Report all your current medicines as well as your medical conditions to your doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Canmab 440 Injection works by stopping the growth of cancer cells in your body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

HER2 inhibitors, Anticancer drug

Schedule

Schedule H

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 31 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/103792s5250lbl.pdf>

Dailymed.nlm.nih.gov. 2021. DailyMed - HERCEPTIN- trastuzumab injection, powder, lyophilized, for solution. [online] Available at: < [Accessed 31 December 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=492dbdb2-077e-4064-bff3-372d6af0a7a2>

Medicines.org.uk. 2021. Kanjinti 150 mg powder for concentrate for solution for infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 31 December 2021].

https://www.medicines.org.uk/emc/product/9233/smpc#CLINICAL_PRECAUTIONS>

Drugs, H., 2021. Trastuzumab Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 31 December 2021].

https://medlineplus.gov/druginfo/meds/a699019.html>
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Information on this page was last updated on 3 Mar 2022

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.