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Bestocin 250 MG Injection

Manufactured byBestochem Formulations (India) Ltd.
ContainsErythromycin
Description
Bestocin 250 MG Injection is a macrolide antibiotic used to treat bacterial infections of the lungs, skin, bones, stomach, and intestine. This medicine kills or stops the growth of bacteria causing the infection. It is not effective against infections caused by viruses. If you are not able to take erythromycin by mouth (oral forms), Bestocin 250 MG Injection is used for treatment. It is administered into your vein by a health care professional in a hospital or clinic. This antibiotic should only be used to treat or prevent infections that are caused by bacteria. Once an antibiotic is started, it is always recommended to finish the entire course of treatment. Common side effects of Bestocin 250 MG Injection are diarrhoea, muscle pain, headache, weakness, skin rash, and pain at the injection site. How long do erythromycin side effects last? Well, these side effects are temporary and they self-resolve within a few days after the treatment. Use Bestocin 250 MG Injection cautiously in individuals with liver problems.

Side effects

Major & minor side effects for Bestocin 250 MG Injection

  • Skin blistering
  • Chills
  • Diarrhoea
  • Fast heartbeat
  • Skin rash
  • Muscle or joint pain
  • Chest tightness
  • Stomach pain
  • Loss of appetite
  • Weight loss
  • Dizziness
  • Difficulty in breathing
  • Swelling of the face, lips or throat
  • Headache
  • Nausea and Vomiting
  • Dark urine
  • Pain at the injection site

Uses of Bestocin 250 MG Injection

What is it prescribed for?

  • Lung infections
  • Acute otitis media
  • Bronchitis
  • Pharyngitis/Tonsilitis
  • Skin and soft tissue infections
  • Stomach and intestinal infections
  • Diptheria
  • Pelvic Inflammatory Disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    You will start to feel better in 3 to 5 days after receiving erythromycin injection.
  • How long do the effects of this medicine last?
    The duration of action for erythromycin injection is not clinically determined.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Bestocin 250 MG Injection
  • Can this medicine be taken during pregnancy?
    Bestocin 250 MG Injection is generally safe in pregnancy to treat bacterial infections. It is not known to cause any harm to the fetus. However, in early pregnancy, it can increase the risk of major birth defects and therefore should only be used upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    Bestocin 250 MG Injection is not known to be harmful in breastfeeding women. It passes into breast milk in very low levels. Hence it is acceptable for use in nursing mothers upon your doctor's recommendation.

Allergy

Avoid using Bestocin 250 MG Injection if you are previously allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Liver impairment

Do not use Bestocin 250 MG Injection in patients with a history of cholestatic jaundice (a condition of reduced bile flow from the liver to the small intestine) or impaired liver function associated with prior use of this medicine.

Statins

The combined use of Bestocin 250 MG Injection and statins (cholesterol medicines) such as atorvastatin, simvastatin, etc., cause serious side effects on muscles such as pain, tenderness, or weakness.
Warnings for special population

Pregnancy

Bestocin 250 MG Injection is generally safe in pregnancy to treat bacterial infections. It is not known to cause any harm to the fetus. However, in early pregnancy, it can increase the risk of major birth defects and therefore should only be used upon your doctor's recommendation.

Breast-feeding

Bestocin 250 MG Injection is not known to be harmful in breastfeeding women. It passes into breast milk in very low levels. Hence it is acceptable for use in nursing mothers upon your doctor's recommendation.
General warnings

Antibiotic resistance

The entire course of treatment with Bestocin 250 MG Injection should be completed, even if the condition gets better to avoid antibiotic resistance.

Diarrhoea

Bestocin 250 MG Injection can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor if you experience severe diarrhoea while receiving this medicine.

Allergy

Avoid using Bestocin 250 MG Injection if you have a known allergy to it or other macrolides. Seek immediate medical attention if the patient experiences any allergic symptoms like rashes, itching, nausea, vomiting, swelling of lips, hands, and feet.

Missed Dose

Since Bestocin 250 MG Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since Bestocin 250 MG Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the chances of an overdose are very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clonazepam

Amiodarone

Pimozide

Alprazolam

Verapamil

Clobazam

Atorvastatin

Ceritinib

Ketoconazole

Disease interactions

Impaired liver function

Patients with liver diseases need special consideration while using Bestocin 250 MG Injection due to the risk of liver damage. Dose adjustment should be done based on the clinical condition.

QT Prolongation

Bestocin 250 MG Injection may cause heart rhythm problem called prolonged QT intervals (an electrical heartbeat disturbance) in some patients who are taking heart medications. It may result in fast, rapid, and irregular heartbeats.

Myasthenia Gravis

Myasthenia gravis is a skeletal muscle weakness condition characterized by severe weakness of any of the muscles under your voluntary control, including the arms and legs. Use Bestocin 250 MG Injection with extreme caution in patients with myasthenia gravis since it may get worsen.
Food interactions
Information not available.
Lab interactions
Information not available.
Bestocin 250 MG Injection should be administered by a qualified healthcare professional in the clinical or hospital setting. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Bestocin 250 MG Injection works by stopping the bacterial protein synthesis that is essential for its growth. Thus it kills or stops the growth of bacteria.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Macrolides, Antibiotics

Schedule

Schedule H

Medsafe.govt.nz. 2020. [online] Available at: < [Accessed 21 December 2020].

https://www.medsafe.govt.nz/Profs/Datasheet/e/ErythrocinIVinj.pdf>

Medicines.org.uk. 2020. Erythromycin 1G Powder For Solution For Infusion - Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: < [Accessed 21 December 2020].

https://www.medicines.org.uk/emc/product/7311/smpc>

Medlineplus.gov. 2020. Erythromycin: Medlineplus Drug Information. [online] Available at: < [Accessed 21 December 2020].

https://medlineplus.gov/druginfo/meds/a682381.html>

Pdf.hres.ca. 2020. [online] Available at: < [Accessed 30 December 2020].

https://pdf.hres.ca/dpd_pm/00041085.PDF>

Mri.cts-mrp.eu. 2020. [online] Available at: < [Accessed 30 December 2020].

http://mri.cts-mrp.eu/download/DK_H_2285_001_FinalPL.pdf>
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Information on this page was last updated on 1 Feb 2021

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