Erythromycin

Description

Erythromycin is a macrolide antibiotic which is used to treat infections caused by the bacteria in the lungs, throat, and ear. Inform the doctor if you are allergic to this medicine.

Side effects

Major & minor side effects for Erythromycin

  • Skin blistering
  • Chills
  • Diarrhea
  • Dizziness
  • Fast heartbeat
  • Skin rash
  • Muscle or joint pain
  • Chest tightness
  • Abdominal pain
  • Loss of appetite
  • Weight loss

Uses of Erythromycin

What is it prescribed for?

  • Pneumonia
  • Ear Infection (Otitis Media)
  • Bronchitis
  • Pertussis
  • Prophylaxis for Rheumatic Fever
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 3 hours of oral administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 4 to 6 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    Clear data is not available regarding the use of this medicine in pregnant women. Use only if the benefits outweigh the risks and if no other safer alternative is available.
  • Usage while breast-feeding?
    A small amount of this medicine is excreted in human breast milk. Use only if benefits outweigh the risks and if no other safer alternative is available. Monitoring of diarrhea, thrush and diaper rash is necessary.

Allergy

Avoid taking this medicine if you have a known allergy to it or any other macrolides.
Warnings for special population

Pregnancy

Clear data is not available regarding the use of this medicine in pregnant women. Use only if the benefits outweigh the risks and if no other safer alternative is available.

Breast-feeding

A small amount of this medicine is excreted in human breast milk. Use only if benefits outweigh the risks and if no other safer alternative is available. Monitoring of diarrhea, thrush and diaper rash is necessary.
General warnings

Allergy

Avoid taking this medicine if you have a known allergy to Erythromycin or other macrolides. Seek immediate medical attention if the patient experiences any allergic symptoms like rashes, itching, nausea, vomiting, swelling of lips, hands, and feet.

Drug-resistance

Usage of Erythromycin without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Clostridium difficile-associated Diarrhea

Avoid if you experience severe diarrhea after receiving Erythromycin. As antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine which promotes the growth of bacteria called Clostridium difficile.

Impaired liver function

Erythromycin may increase the liver enzymes and may cause cholestatic hepatitis, with or without jaundice. This medicine should be used with caution in the patients with the history of liver disease. Dose adjustments are to be made based on the severity of liver injury.

QT prolongation

Erythromycin should be used with caution in the patients receiving QT prolongation medications as it can increase the risk of arrhythmia. Frequent monitoring of heart function is necessary and an alternate medicine should be considered.

Myasthenia Gravis

Erythromycin should be used with caution in the patients with the history of Myasthenia Gravis as it may aggravate the weakness in these patients.

Missed Dose

The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clonazepam

Amiodarone

Pimozide

Ethinyl Estradiol

Disease interactions

Impaired liver function

Erythromycin should be used with caution in the patients with a history of liver disease. Frequent monitoring of liver function tests is necessary. Dose adjustments are to be made based on the severity of liver injury.

QT Prolongation

Inform your doctor if you have arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs and anti-arrhythmic drugs.

Myasthenia Gravis

Erythromycin should be used with caution in the patients with the history of Myasthenia Gravis as it may aggravate the weakness in these patients. Dose adjustments or an alternate medicine should be prescribed based on the medical condition.
Food interactions
Take Erythromycin at least 30 minutes before or 2 hours after meals. Consumption of grapefruit juice is not recommended as it may increase the concentration of Erythromycin and can cause undesired effects.
Lab interactions
Information not available.
Take Erythromycin as advised by your doctor. You may take this drug with or without food and do not take in larger amounts than advised.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Erythromycin is used to treat bacterial infections by interfering with the bacterial protein synthesis.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Macrolides

Schedule

Schedule H

[Internet]. 2017 [cited 31 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/28987

DailyMed - erythromycin capsule, coated pellets [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 31 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c3f7cd94-d842-4f6b-a582-a38c751a790a

Erythromycin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 31 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682381.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 31 March 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 31 March 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~Q4NzZo:1

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Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.