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Azafab Injection
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Azafab Injection

Manufactured byPANACEA BIOTEC LTD
ContainsAzacitidine
Description
Azafab Injection is used for the treatment of myelodysplastic syndrome, a group of cancers that affect the production of blood cells. This medicine works by enhancing the bone marrow for the production of normal blood cells. It also helps in killing the abnormal cells in the bone marrow. Azafab Injection can cause side effects like nausea, vomiting, cough, headache, etc. Consult your doctor if these side effects are worsening or getting persistent. Avoid driving vehicles and operating machines after receiving this medicine as it can make you feel drowsy. Azafab Injection is administered by a qualified healthcare professional in a clinic or a hospital. Your dose and duration of the treatment will be decided on the basis of the severity of your condition. Do not stop receiving this medication without consulting your doctor as your symptoms could reoccur. Azafab Injection is not recommended if you are allergic to it. Inform all your current medications and pre-existing medical conditions to your doctor before receiving this medicine. This will help your doctor to adjust your dose for avoiding any side effects. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Azafab Injection

Myaza Injection
Mylan Pharmaceuticals

Side effects

Major & minor side effects for Azafab Injection

  • Nausea and vomiting
  • Dizziness
  • Chest pain
  • Difficulty in breathing
  • Fast heartbeat
  • Headache
  • Cough
  • Unusual tiredness or weakness
  • Bleeding gums
  • Blurred vision

Uses of Azafab Injection

What is it prescribed for?

  • Myelodysplastic syndrome
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Azafab Injection to show its action is not clinically established.
  • How long do the effects of this medicine last?
    Azafab Injection can remain in your body for 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Azafab Injection.
  • Can this medicine be taken during pregnancy?
    Azafab Injection is highly unsafe during pregnancy as it can harm your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of relevant safety information, Azafab Injection is not recommended for use while breastfeeding. Consult your doctor if you are breastfeeding.

Allergy

Azafab Injection is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Liver tumours

Azafab Injection is not recommended for use in you have an advanced tumour (a solid mass of tissue that forms when abnormal cells group together) in your liver, as it may worsen your condition.
Warnings for special population

Pregnancy

Azafab Injection is highly unsafe during pregnancy as it can harm your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Due to the lack of relevant safety information, Azafab Injection is not recommended for use while breastfeeding. Consult your doctor if you are breastfeeding.
General warnings

Anaemia

Anaemia is a condition in which the number of red blood cells or the haemoglobin concentration within them is lower than normal. Azafab Injection can cause anaemia in some people. Therefore, your doctor will closely monitor your blood cells while you are receiving this medicine.

Driving or operating machinery

Azafab Injection may cause dizziness, fainting, loss of balance, etc. Therefore, avoid driving vehicles or operating machines while receiving this medicine.

Tumour lysis syndrome

Tumour lysis syndrome (TLS) is a condition that occurs when a large number of cancer cells die within a short period, releasing their contents into the blood. Azafab Injection should be used with caution since it may increase the risk of tumour lysis syndrome. Your doctor can adjust your dose or replace it with another medicine if required.

Women with child bearing potential

Azafab Injection is not recommended for use in pregnant women unless absolutely necessary due to the increased risk of fetal harm. Female patients of child-bearing potential should always use at least 2 methods of reliable birth control to avoid pregnancy during treatment with this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Missed Dose

Since Azafab Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.

Overdose

Since Azafab Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Leflunomide

BCG vaccine

Adalimumab

Clozapine

Disease interactions

Kidney Disease

Azafab Injection is filtered by your kidneys. If you have kidney problems, this medicine will not get filtered properly, therefore increasing the risk of toxicity. Your doctor can adjust the dose while monitoring your condition closely or suggest another medicine if required.

Liver Disease

Azafab Injection is broken down and absorbed in the liver. Therefore, a damaged liver will not break it down properly, resulting in toxicity. Your doctor can adjust your dose or replace it with another medicine according to your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Azafab Injection is usually administered by a qualified healthcare professional in the hospital or clinical setting. Inform the doctor if you have a known allergy to this medicine. Consult your doctor if you experience any change of colour in your urine or any other side effects.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Azafab Injectionworks by enhancing the bone marrow for the production of normal blood cells. It also helps in killing the abnormal cells in the bone marrow.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous antineoplastics

Schedule

Schedule H

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 1 March 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/050794s031lbl.pdf>

Medicines.org.uk. 2022. Vidaza 25 mg/ml powder for suspension for injection - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 1 March 2022].

https://www.medicines.org.uk/emc/product/6468/smpc#>

Bioline.org.br. 2022. [online] Available at: < [Accessed 1 March 2022].

http://www.bioline.org.br/pdf?ph05113>
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Information on this page was last updated on 9 Jan 2023

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