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Angiotec 500 Mg Tablet

Manufactured by: Glaxosmithkline Pharmaceuticals Ltd.
Composition: Ranolazine
Prescription Required: Yes
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Description

Angiotec 500 Mg Tablet is used to relieve chest pain in conditions like chronic angina. Proper lifestyle modifications are necessary along with this medicine for a speedy recovery. Elderly and low body weight patients should use this medicine with caution due to the increased risk of undesired effects.

Side effects

Major & minor side effects for Angiotec 500 Mg Tablet

  • Dizzinesssevere
  • Ringing or buzzing in the earssevere
  • Chest tightnesssevere
  • Headachesevererare
  • Blurred visionsevererare
  • Constipation
  • Dry mouth
  • Stomach pain
  • Loss of strengthrare
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Angiotec 500 Mg Tablet

Onset of action

The amount of time needed for this medicine to show its effect is not clinically established. However, it takes 2 to 6 hours to reach maximum concentration in the blood.

Duration of effect

This medicine remains active in the body for an average duration of 21 hours after an oral dose.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Substitutes

List of substitutes for Angiotec 500 Mg Tablet

Below is the list of medicines, which have the same composition, strength and form as Angiotec 500 Mg Tablet, and hence can be used as its substitute.
Ranolaz 500 Mg Tablet
Torrent Pharmaceuticals Ltd.
Ranoplan 500 Mg Tablet
Mankind Pharmaceuticals Ltd.
Ranx 500 Mg Tablet
Unichem Laboratories Ltd.
Ranz 500 Mg Tablet
Intas Pharmaceuticals Ltd.
Rolazin 500 Mg Tablet
Macleods Pharmaceuticals Pvt. Ltd.

What is it prescribed for?

Uses of Angiotec 500 Mg Tablet

  • Angina Pectoris

    Angiotec 500 Mg Tablet is used to relieve chest pain in patients with conditions like Angina pectoris.

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When not to use?

Contraindications of Angiotec 500 Mg Tablet

  • Liver disease

    This medicine is not recommended for use in patients with a severe liver disease.
  • Drug interaction

    This medicine is not recommended for use in patients receiving strong CYP3A inhibitors like ketoconazole, clarithromycin, nelfinavir and CYP3A inducers like carbamazepine, phenobarbital, phenytoin, rifampin, etc. due to alteration in Angiotec 500 Mg Tablet blood levels.

Dosage

  • Missed Dose

    The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.
  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Metforminmoderate
  • Phenytoinsevere
  • Digoxinmoderate
  • Atorvastatinsevere

Disease interactions

  • Liver Disease

    severe
    Angiotec 500 Mg Tablet is not recommended for use in patients with a history of liver disease or active liver disease due to an increase in the risk of serious adverse effects. An alternate treatment option should be considered based on the clinical condition.
  • Kidney disease

    moderate
    Angiotec 500 Mg Tablet should be used with caution in patients with a history of kidney disease or active kidney disease due to an increase in the risk of serious adverse effects. An alternate treatment option should be considered based on the clinical condition.
  • QT Prolongation

    moderate
    This medicine should be used with caution in patients with a history of prolonged QT interval and patients using medicines that prolong QT interval. Appropriate dose adjustments should be made under your doctor's supervision.

Food interactions

  • Consumption of grapefruit juice while taking Angiotec 500 Mg Tablet is not recommended due to an increase in the risk of dizziness, fast heartbeat, and fainting. Any such symptoms should be reported to the doctor on priority.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Angiotec 500 Mg Tablet as advised by the doctor. Do not consume larger quantities than prescribed. It is advised that you inform the doctor if you have a history of liver or kidney disease. Proper lifestyle modifications should be adopted along with the medicine to prevent further complications. Report to the doctor if you experience any undesired effects while receiving the medicine.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

General warnings

  • Elderly population

    - Angiotec 500 Mg Tablet should be used with caution in patients more than 60 years of age due to an increase in the risk of undesired effects. Close monitoring of kidney function is necessary. The dose should be adjusted based on the kidney function.
  • Low body weight

    - Angiotec 500 Mg Tablet should be used with caution in patients less than 60 kg of body weight due to an increase in the risk of undesired effects. The dose should be adjusted based on the body weight.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

How it works

It works by relaxing the heart muscles and thus relieves the chest pain.

Legal Status

Approved
Approved
Approved
Unknown

Classification

Category
Antianginal agents
Schedule
Schedule H

References

  • [Internet]. 2017 [cited 14 July 2017]. Available from: https://www.medicines.org.uk/emc/medicine/21402
  • DailyMed - Ranolazine tablet, film coated, extended release [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 14 July 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8d442b8c-97a8-40a9-8603-f9cd0542cedc
  • [Internet]. Gilead.com. 2018 [cited 5 January 2018]. Available from: http://www.gilead.com/~/media/Files/pdfs/medicines/cardiovascular/ranexa/ranexa_pi.ashx

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Information on this page was last updated on 5 Jan 2018

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.