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Oleanz Forte Tablet

Manufactured bySUN PHARMA LABORATORIES LTD
ContainsOlanzapine (10 mg) + Fluoxetine (20 mg)
CURRENTLY UNAVAILABLE

Description

Oleanz Forte Tablet is a combination medicine used for the treatment of resistant depression. This medicine is not recommended for use in patients less than 18 years of age.
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Substitutes

List of substitutes for Oleanz Forte Tablet

Side effects

Major & minor side effects for Oleanz Forte Tablet

Skin rash

Restlessness

Fever or chills

Muscle or joint pain

Anxiety

Increased sweating

Dry mouth

Decreased appetite

Abnormal dreams

Frequent urination

Changes in vision

Convulsions (seizures)

Orthostatic Hypotension

Weight gain

Headache

Sleepiness

Increase in body fat and cholesterol

Dizziness

Uncontrolled muscle movements

Chest pain

Uses of Oleanz Forte Tablet

What is it prescribed for?

Resistant Depression

This medicine is used for the treatment of resistant depression, a type of major depressive disorder (MDD) that does not respond adequately to appropriate courses of at least 2 anti-depressants.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The peak effect of this medicine can be observed within 5 to 8 hours of administration of the dose.

  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as difficulty concentrating, dizziness, confusion, drowsiness, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to fluoxetine, any other serotonin reuptake inhibitors, olanzapine, or any other inactive ingredients present along with these medicines.

Monoamine oxidase inhibitors

This medicine is not recommended for use in patients who have taken monoamine oxidase inhibitors within the last 14 days due to the increased risk of serious adverse effects.

Thioridazine

This medicine is not recommended for use in patients undergoing therapy with thioridazine due to the increased risk of worsening of the patient's condition.

Pimozide

This medicine is not recommended for use in patients undergoing therapy with pimozide due to the increased risk of worsening of the patient's condition.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

Suicidal thoughts

This medicine should be used with caution due to the increased risk of suicidal thoughts. Close monitoring of the patients for any change in behavior or mood is recommended. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Abnormal bleeding

This medicine should be used with caution in the patients undergoing treatment with NSAIDs, aspirin, or warfarin due to an increase in the risk of excessive bleeding. Report any unusual bleeding or bruising to the doctor immediately. More frequent clinical monitoring and/or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Changes in weight

This medicine is known to cause either weight loss or weight gain. Inform the doctor if you experience any changes in the body weight. Close monitoring of body weight is recommended during treatment with this medicine. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Diabetes

This medicine may alter the blood glucose levels in diabetic patients. Close monitoring of blood glucose levels is recommended for such patients. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Discontinuation of treatment

Do not stop the use of this medicine suddenly since this may cause withdrawal symptoms such as nausea, headache, anxiety, dizziness, irritability, etc. Gradual dose reduction should be done under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function and/or replacement with a suitable alternative may be required based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests and/or replacement with a suitable alternative may be required based on the clinical condition.

Muscular Disorders

This medicine may cause muscular disorders in some patients. Any incidence of ticks or uncontrolled muscle movements, fever, dizziness, weakness in muscles, etc. should be reported to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition of the patient.

Use in pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as difficulty concentrating, dizziness, confusion, drowsiness, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Acarbose

Amlodipine

Cetirizine

Diazepam

Tramadol

Atropine

Diuretics

Monoamine oxidase inhibitors

Disease interactions

Glaucoma

This medicine should be used with caution in patients with a known history of glaucoma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Diabetes

This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood sugar levels is recommended for such patients. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function tests and/or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Seizure disorders

This medicine should be used with caution in patients with a history of seizure disorders since it may worsen the patient's condition. Close monitoring of the patient is necessary during treatment with this medicine. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Renal Dysfunction

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function and/or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neuroleptic Malignant Syndrome (NMS)

This medicine is not recommended for use in patients with a known history of neuroleptic malignant syndrome due to the increased risk of worsening of the patient's condition. If the medicine is used, any unusual symptoms should be reported to the doctor on priority. Replacement with a suitable alternative should be considered based on the clinical condition.

Tardive Dyskinesia

This medicine is not recommended for use in patients with a known history of tardive dyskinesia since it may worsen the patient's condition. This risk is especially higher in the elderly patients and female patients. Therapy should be discontinued if symptoms such as uncontrolled movements involving the tongue, mouth, lips, jaws, etc. are experienced. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine with or without food. Do not take in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor since this may cause withdrawal symptoms.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Olanzapine increases the levels of certain specific chemicals in the brain to exert its antidepressant action. Fluoxetine increases the levels of a chemical substance called serotonin in the brain; this helps in maintaining normal brain function and reduces the symptoms of depression. Their combination is thus better effective than monotherapy for the treatment of resistant depression.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Atypical antipsychotics, Selective Serotonin reuptake inhibitors , Psychotherapeutic combinations

Schedule

Schedule H

Fluoxetine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 31 October 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a689006.html

Olanzapine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 28 February 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601213.html

Fluoxetine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 31 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB00472

Olanzapine | C17H20N4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 28 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/4585

[Internet]. Accessdata.fda.gov. 2018 [cited 5 March 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021520s022lbl.pdf

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Information on this page was last updated on 11 Jul 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.