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Fibral EZ Tablet
Manufactured byMICRO LABS LTD
ContainsFenofibrate (200 mg) + Ezetimibe (10 mg)
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Description
Fibral EZ Tablet is a combination medicine which may be used for the treatment of combined hyperlipidemia, a condition characterized by increased blood levels of bad cholesterol (LDL) and triglycerides and decreased blood levels of good cholesterol (HDL). Patients are advised to maintain a strict exercise and diet regimen along with this medicine to obtain the best possible effect.
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Substitutes
List of substitutes for Fibral EZ Tablet
Side effects
Major & minor side effects for Fibral EZ Tablet
Headache
Dizziness
Sore throat
Runny Nose
Sneezing
Joint pain
Loss of appetite
Cough
Chills and fever
Itching and skin rash
Nausea and Vomiting
Shortness of breath
Weakness
Stuffy Nose
Increased sensitivity of the skin to sunlight
Uses of Fibral EZ Tablet
What is it prescribed for?
Combined hyperlipidemia
This medicine may be used to treat combined hyperlipidemia, a condition characterized by increased blood levels of bad cholesterol (LDL) and triglycerides and decreased blood levels of good cholesterol (HDL) in the blood.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for this medicine to show its action is not clinically established.How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit-forming tendencies were reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to fenofibrate, other fibric acid derivatives, ezetimibe, or any other inactive ingredients present in the formulation.
Active liver disease
This medicine is not recommended for use in patients with active liver diseases or any abnormality in the liver function tests due to the increased risk of severe adverse effects.
Severe renal impairment
This medicine is not recommended for use in patients with severe renal impairment due to the increased risk of serious adverse effects.
Gallbladder disease
This medicine is not recommended for use in patients with a known history of gallbladder diseases due to the increased risk of gallbladder stones.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Coumarin Anticoagulants
This medicine should be used with extreme caution in patients receiving coumarin anticoagulants such as warfarin due to the increased risk of excessive bleeding. Close monitoring of International Normalized Ratio (INR) is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Use in Children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.
Cholelithiasis
This medicine is not recommended for use in patients with gallbladder diseases due to the increased risk of gallbladder stones. Replacement with a suitable alternative should be considered based on the clinical condition.
Hematologic Changes
This medicine should be used with caution due to the increased risk of a decrease in the hemoglobin, hematocrit, and white blood cell count levels. Close monitoring of complete blood count is recommended in patients receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Increase in serum creatinine levels
This medicine may increase serum creatinine levels. Close monitoring of renal function is recommended in patients receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Muscle degradation and Rhabdomyolysis
This medicine may cause muscle breakdown and rhabdomyolysis in some patients, a condition which can be fatal. This may cause symptoms such as severe tiredness and weakness. This risk is especially higher in the elderly population and in patients with active muscle disorders. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition.
Driving or Operating machinery
Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Cyclosporine
Cholestyramine
Hypoglycemic agents
Statin agents
Disease interactions
Rhabdomyolysis
This medicine is not recommended for use in patients with a known history of Rhabdomyolysis due to the increased risk of renal failure and death. Replacement with a suitable alternative should be considered under your doctor's supervision.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Fenofibrate increases the natural lipid breakdown process with the help of the enzyme lipoprotein lipase. This removes the bad cholesterol (LDL) and triglycerides from the blood and increases the levels of good cholesterol (HDL). Ezetimibe works by reducing or stopping the absorption of cholesterol through the small intestine. Their combination is thus better effective than monotherapy in the treatment of combined hyperlipidemia.
Legal Status
Classification
Category
Fibric acid derivatives, Cholesterol absorption inhibitors
Schedule
Schedule H
Ezetimibe tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 23 August 2017]. Available from:
Ezetimibe: DrugBank [Internet]. Drugbank.ca. 2017 [cited 23 August 2017]. Available from:
Ezetimibe: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 23 August 2017]. Available from:
DailyMed - fenofibrate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 4 August 2017]. Available from:
[Internet]. 2017 [cited 4 August 2017]. Available from:
Fenofibrate: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 4 August 2017]. Available from:
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Information on this page was last updated on 24 Jun 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.