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Amitor 25 MG Tablet

Manufactured by: Torrent Pharmaceuticals Ltd.
Composition: Amitriptyline
Prescription Required: Yes
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Description

Amitor 25 MG Tablet is an effective medicine, used to treat depression. It belongs to a class of medicines known as tricyclic antidepressants. It acts by altering the levels of certain chemicals in the brain.

Side effects

Major & minor side effects for Amitor 25 MG Tablet

  • Headache
  • Nausea and Vomiting
  • Constipation or diarrhea
  • Blurred vision
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Unexpected weight gain or loss
  • Chest pain and discomfortsevere
  • Shortness of breathsevere
  • Weakness in one side of the bodysevererare
  • Slurred speechsevererare
  • Seizuressevererare
  • Decreased sexual urge
  • Unusual bleedingsevererare
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Amitor 25 MG Tablet

Onset of action

The effect of this medicine can be observed within 3-6 weeks of administration.

Duration of effect

The effect of this medicine lasts for an average duration of 4-7 weeks after onset of action. However, it is subject to variation based on a patient's response to the medicine after administration.

Safe with alcohol?

moderate
You should restrict or minimize the use of alcohol while taking this medicine. Symptoms like sleepiness, excessive sweating, muscle stiffness and change in pulse should be reported to the doctor on priority.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine should be used by pregnant women only when the benefits outweigh the risk associated with usage. This medicine can cause harmful effects on fetus. Hence, you are advised to consult your doctor before taking this medicine.

Usage while breast-feeding?

This medicine should not be used by women who are breastfeeding. If it is absolutely necessary to take this medicine then you should stop breastfeeding. Consult your doctor before using this medicine.

Substitutes

List of substitutes for Amitor 25 MG Tablet

Below is the list of medicines, which have the same composition, strength and form as Amitor 25 MG Tablet, and hence can be used as its substitute.
Amitone 25 MG Tablet
Intas Pharmaceuticals Ltd.
Eliwel 25 MG Tablet
Sun Pharma Laboratories Ltd.
Normaline 25 MG Tablet
Mankind Pharmaceuticals Ltd.
Sarotena 25 MG Tablet
Lundbeck India Pvt. Ltd.
Tryptomer 25 MG Tablet
Wockhardt Ltd.

What is it prescribed for?

Uses of Amitor 25 MG Tablet

  • Depression

    Amitor 25 MG Tablet is used to relieve symptoms of depression. These symptoms may include sadness, loss of interest, irritability and sleeplessness.
  • Migraine prevention

    Amitor 25 MG Tablet is also used to prevent the onset of migraine headaches in some patients.
  • Bed wetting

    Amitor 25 MG Tablet may sometimes be used to treat a condition in children characterized by bed wetting while sleeping.

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When not to use?

Contraindications of Amitor 25 MG Tablet

  • Allergy

    Amitor 25 MG Tablet is not recommended for use if you have a history of allergy to it or any other component of the medicine.
  • Monoamine oxidase inhibitors

    Amitor 25 MG Tablet should be used with extreme caution along with any medicine belonging to the class Monoamine oxidase inhibitors. Some medications belonging to this class are Selegiline and Isocaboxazid.
  • Cisapride

    Amitor 25 MG Tablet is not recommended for use along with Cisapride due to an increased risk of side effects on heart and blood vessels.
  • Heart attack

    Amitor 25 MG Tablet is not recommended for use if the patient is recovering from a recent heart attack.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.
  • Overdose

    Contact a doctor immediately if an overdose is suspected. Symptoms of overdose may include a change in pulse rates, severe drowsiness, confusion, vomiting, hallucinations, convulsions, and fainting. Immediate medical intervention may be required if the overdose symptoms are severe.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - Use of alcohol can change the response of Amitor 25 MG Tablet and can cause some serious side effects on the body.
  • Instructions

    - You should restrict or minimize the use of alcohol while taking this medicine. Symptoms like sleepiness, excessive sweating, muscle stiffness and change in pulse should be reported to the doctor on priority.

Interaction with Medicine

  • Cisapridesevere
  • Clozapinesevere
  • Fluoxetinesevere
  • Linezolidsevere
  • Ondansetronsevere
  • Selegelinesevere
  • Phenylephrinesevere

Disease interactions

  • Heart Disease

    severe
    Amitor 25 MG Tablet should be used with caution in patients suffering from heart disease like heart failure, stroke, heart block etc. A fall in blood pressure, change in pulse, dizziness and other associated complications should be reported to the doctor. It is advised to not take this medicine if the patient has recently suffered a heart attack.
  • Pheochromocytoma

    severe
    Amitor 25 MG Tablet should be administered with extreme caution in patients suffering from Pheochromocytoma, the risk of severe to fatal change in blood pressure is very high. Suitable dose adjustment and clinical monitoring of the symptoms is recommended in such cases.
  • Seizure disorders

    severe
    Amitor 25 MG Tablet should be used with caution in patients having a seizure disorder. Seizures may be caused due to a disease, some other medicine, head injury in the past etc. Using this medicine can cause more frequent and severe episodes of seizures.
  • Diabetes

    moderate
    Amitor 25 MG Tablet should be used with caution if you have diabetes as the risk of changes in blood sugar levels are very high. You should get your blood sugar levels checked more frequently while using this medicine.
  • Glaucoma

    moderate
    Amitor 25 MG Tablet should be used with caution if you have glaucoma. Use of this medicine can worsen the symptoms of both closed and open angle glaucoma.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Amitor 25 MG Tablet as instructed by the doctor. Follow all the labeled instructions while taking this medicine. Ensure that the right quantity of medicine is consumed for the prescribed duration only. Initial use may worsen the symptoms of depression and it may take up to 20-30 days for any improvement to happen. Usage should not be stopped abruptly.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine should be used by pregnant women only when the benefits outweigh the risk associated with usage. This medicine can cause harmful effects on fetus. Hence, you are advised to consult your doctor before taking this medicine.
  • Breast-feeding

    - This medicine should not be used by women who are breastfeeding. If it is absolutely necessary to take this medicine then you should stop breastfeeding. Consult your doctor before using this medicine.

General warnings

  • Sedation

    - Use of this medicine can cause moderate to severe sedation and impairment of physical abilities. You should avoid work that requires a high level of mental alertness while using this medicine.
  • Hypotension

    - Use of this medicine can cause a fall in blood pressure, and hence, caution is advised.
  • Liver disease

    - This medicine should be used with caution if you are suffering from impaired liver functioning. Report all such conditions to the doctor before receiving this medicine.
  • Kidney disease

    - This medicine should be used with caution if you are suffering from impaired kidney function. Report all such conditions to the doctor before receiving this medicine.
  • Bipolar disorder

    - This medicine should be used with extreme caution in patients suffering from bipolar disorder. Symptoms of mania and depression can worsen upon usage of this medicine. Consult your doctor and report the incidence of bipolar depression or mania before receiving this medicine.
  • Suicidal tendencies

    - Use of this medicine is reported to provoke suicidal thoughts and increased suicidal tendencies, especially in young patients. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals.
  • Benign prostatic hyperplasia

    - This medicine should be used with caution if you have an enlarged prostate gland. The symptoms might worsen after using this medicine.
  • Withdrawal symptoms

    - The use of this medicine should not be discontinued abruptly. You may experience withdrawal symptoms especially if you have been using a high dose for a long duration. Do not stop the use of this medicine without consulting your doctor.
  • Other medicine

    - This medicine is known to interact with many other medicines. Report the use of all the medicines including supplements and herbs to the doctor before starting to take Amitor 25 MG Tablet.
  • Pediatric use

    - This medicine should not be used in children below 12 years of age.
  • Surgery

    - Use of this medicine is not recommended if you are planning to undergo a surgery in near future. Consult your doctor in this regard so that it can be discontinued properly.

Other details

  • Food timings: Information not available
  • Administration time: Information not available
  • Sleep inducing: Information not available

How it works

This medicine is believed to work by increasing the concentration of norepinephrine and serotonin which are the two primary chemical messengers in the brain.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Tricyclic antidepressants
Schedule
Schedule H

References

  • Amitriptyline [Internet]. Healthline. 2017 [cited 21 March 2017]. Available from: http://www.healthline.com/health/amitriptyline/oral-tablet?s_con_rec=true&r=01#Interactions3
  • Amitriptyline - FDA prescribing information, side effects and uses [Internet]. Drugs.com. 2017 [cited 21 March 2017]. Available from: https://www.drugs.com/pro/amitriptyline.html
  • amitriptyline Full Prescribing Information, Dosage & Side Effects | CIMS India [Internet]. Mims.com. 2017 [cited 21 March 2017]. Available from: http://www.mims.com/india/drug/info/amitriptyline/?type=full&mtype=generic#Actions
  • Amitriptyline: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 March 2017]. Available from: https://medlineplus.gov/druginfo/meds/a682388.html
  • DailyMed - AMITRIPTYLINE HYDROCHLORIDE- amitriptyline hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 21 March 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1e6d2c80-fbc8-444e-bdd3-6a91fe1b95bd
  • Levate (amitriptyline), dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 21 March 2017]. Available from: http://reference.medscape.com/drug/levate-amitriptyline-342936#0

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Information on this page was last updated on 30 Mar 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.