Amitone 25 MG Tablet

Manufactured byIntas Pharmaceuticals Ltd.
Description

Amitone 25 MG Tablet is an effective medicine, used to treat depression. It belongs to a class of medicines known as tricyclic antidepressants. It acts by altering the levels of certain chemicals in the brain.

Side effects

Major & minor side effects for Amitone 25 MG Tablet

  • Headache
  • Nausea and Vomiting
  • Constipation or diarrhea
  • Blurred vision
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Unexpected weight gain or loss
  • Chest pain and discomfort
  • Shortness of breath
  • Weakness in one side of the body
  • Slurred speech
  • Seizures
  • Decreased sexual urge
  • Unusual bleeding

Uses of Amitone 25 MG Tablet

What is it prescribed for?

  • Depression
  • Migraine prevention
  • Bed wetting
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 3-6 weeks of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 4-7 weeks after onset of action. However, it is subject to variation based on a patient's response to the medicine after administration.
  • Safe with alcohol?
    You should restrict or minimize the use of alcohol while taking this medicine. Symptoms like sleepiness, excessive sweating, muscle stiffness and change in pulse should be reported to the doctor on priority.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine should be used by pregnant women only when the benefits outweigh the risk associated with usage. This medicine can cause harmful effects on fetus. Hence, you are advised to consult your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine should not be used by women who are breastfeeding. If it is absolutely necessary to take this medicine then you should stop breastfeeding. Consult your doctor before using this medicine.

Allergy

Amitone 25 MG Tablet is not recommended for use if you have a history of allergy to it or any other component of the medicine.

Monoamine oxidase inhibitors

Amitone 25 MG Tablet should be used with extreme caution along with any medicine belonging to the class Monoamine oxidase inhibitors. Some medications belonging to this class are Selegiline and Isocaboxazid.

Cisapride

Amitone 25 MG Tablet is not recommended for use along with Cisapride due to an increased risk of side effects on heart and blood vessels.

Heart attack

Amitone 25 MG Tablet is not recommended for use if the patient is recovering from a recent heart attack.
Warnings for special population

Pregnancy

This medicine should be used by pregnant women only when the benefits outweigh the risk associated with usage. This medicine can cause harmful effects on fetus. Hence, you are advised to consult your doctor before taking this medicine.

Breast-feeding

This medicine should not be used by women who are breastfeeding. If it is absolutely necessary to take this medicine then you should stop breastfeeding. Consult your doctor before using this medicine.
General warnings

Sedation

Use of this medicine can cause moderate to severe sedation and impairment of physical abilities. You should avoid work that requires a high level of mental alertness while using this medicine.

Hypotension

Use of this medicine can cause a fall in blood pressure, and hence, caution is advised.

Liver disease

This medicine should be used with caution if you are suffering from impaired liver functioning. Report all such conditions to the doctor before receiving this medicine.

Kidney disease

This medicine should be used with caution if you are suffering from impaired kidney function. Report all such conditions to the doctor before receiving this medicine.

Bipolar disorder

This medicine should be used with extreme caution in patients suffering from bipolar disorder. Symptoms of mania and depression can worsen upon usage of this medicine. Consult your doctor and report the incidence of bipolar depression or mania before receiving this medicine.

Suicidal tendencies

Use of this medicine is reported to provoke suicidal thoughts and increased suicidal tendencies, especially in young patients. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals.

Benign prostatic hyperplasia

This medicine should be used with caution if you have an enlarged prostate gland. The symptoms might worsen after using this medicine.

Withdrawal symptoms

The use of this medicine should not be discontinued abruptly. You may experience withdrawal symptoms especially if you have been using a high dose for a long duration. Do not stop the use of this medicine without consulting your doctor.

Other medicine

This medicine is known to interact with many other medicines. Report the use of all the medicines including supplements and herbs to the doctor before starting to take Amitone 25 MG Tablet.

Pediatric use

This medicine should not be used in children below 12 years of age.

Surgery

Use of this medicine is not recommended if you are planning to undergo a surgery in near future. Consult your doctor in this regard so that it can be discontinued properly.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

Overdose

Contact a doctor immediately if an overdose is suspected. Symptoms of overdose may include a change in pulse rates, severe drowsiness, confusion, vomiting, hallucinations, convulsions, and fainting. Immediate medical intervention may be required if the overdose symptoms are severe.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Use of alcohol can change the response of Amitone 25 MG Tablet and can cause some serious side effects on the body.

Instructions

You should restrict or minimize the use of alcohol while taking this medicine. Symptoms like sleepiness, excessive sweating, muscle stiffness and change in pulse should be reported to the doctor on priority.
Interaction with Medicine

Cisapride

Clozapine

Fluoxetine

Linezolid

Ondansetron

Selegeline

Phenylephrine

Disease interactions

Heart Disease

Amitone 25 MG Tablet should be used with caution in patients suffering from heart disease like heart failure, stroke, heart block etc. A fall in blood pressure, change in pulse, dizziness and other associated complications should be reported to the doctor. It is advised to not take this medicine if the patient has recently suffered a heart attack.

Pheochromocytoma

Amitone 25 MG Tablet should be administered with extreme caution in patients suffering from Pheochromocytoma, the risk of severe to fatal change in blood pressure is very high. Suitable dose adjustment and clinical monitoring of the symptoms is recommended in such cases.

Seizure disorders

Amitone 25 MG Tablet should be used with caution in patients having a seizure disorder. Seizures may be caused due to a disease, some other medicine, head injury in the past etc. Using this medicine can cause more frequent and severe episodes of seizures.

Diabetes

Amitone 25 MG Tablet should be used with caution if you have diabetes as the risk of changes in blood sugar levels are very high. You should get your blood sugar levels checked more frequently while using this medicine.

Glaucoma

Amitone 25 MG Tablet should be used with caution if you have glaucoma. Use of this medicine can worsen the symptoms of both closed and open angle glaucoma.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Amitone 25 MG Tablet as instructed by the doctor. Follow all the labeled instructions while taking this medicine. Ensure that the right quantity of medicine is consumed for the prescribed duration only. Initial use may worsen the symptoms of depression and it may take up to 20-30 days for any improvement to happen. Usage should not be stopped abruptly.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
This medicine is believed to work by increasing the concentration of norepinephrine and serotonin which are the two primary chemical messengers in the brain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

Amitriptyline [Internet]. Healthline. 2017 [cited 21 March 2017]. Available from:

http://www.healthline.com/health/amitriptyline/oral-tablet?s_con_rec=true&r=01#Interactions3

Amitriptyline - FDA prescribing information, side effects and uses [Internet]. Drugs.com. 2017 [cited 21 March 2017]. Available from:

https://www.drugs.com/pro/amitriptyline.html

amitriptyline Full Prescribing Information, Dosage & Side Effects | CIMS India [Internet]. Mims.com. 2017 [cited 21 March 2017]. Available from:

http://www.mims.com/india/drug/info/amitriptyline/?type=full&mtype=generic#Actions

Amitriptyline: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682388.html

DailyMed - AMITRIPTYLINE HYDROCHLORIDE- amitriptyline hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 21 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1e6d2c80-fbc8-444e-bdd3-6a91fe1b95bd

Levate (amitriptyline), dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 21 March 2017]. Available from:

http://reference.medscape.com/drug/levate-amitriptyline-342936#0
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