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Amedil 4 MG Injection

Manufactured byGujarat Terce Laboratories Ltd.
ContainsOndansetron
Description

Amedil 4 MG Injection is an antiemetic agent used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. This medicine is not recommended for use unless prescribed by your physician.

Side effects

Major & minor side effects for Amedil 4 MG Injection

  • Headache
  • Constipation
  • Fatigue
  • Chest pain
  • Dizziness
  • Low blood pressure (hypotension)
  • Seizures
  • Hiccups

Uses of Amedil 4 MG Injection

What is it prescribed for?

  • Chemotherapy induced nausea and vomiting
  • Post operative nausea and vomiting
  • Radiation induced nausea and vomiting
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The peak effect of this medicine can be observed within 30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ondansetron or any other inactive ingredients present in the formulation.

Apomorphine

This medicine is not recommended for use in patients who are concomitantly taking apomorphine due to the increased risk of lightheadedness and loss of consciousness.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Serotonin Syndrome

This medicine should be used with caution since it may increase the risk of serotonin syndrome. This risk is especially high in patients who are concomitantly taking serotonergic drugs. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Carbamazepine

Phenytoin

Amiodarone

Cyclophosphamide

Disease interactions

QT Prolongation

This medicine should be used with extreme caution in patients with prolonged QT due to the increased risk of worsening of the patient's condition. Regular monitoring of electrolyte levels and kidney function tests are necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine blocks the action of chemicals (serotonin) in the body that can trigger nausea and vomiting.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

5HT3 receptor antagonists

Schedule

Schedule H

[Internet]. Medsafe.govt.nz. 2019 [cited 18 September 2019]. Available from:

https://www.medsafe.govt.nz/profs/Datasheet/o/ondansetronkabisol.pdf

[Internet]. Pharma.us.novartis.com. 2019 [cited 18 September 2019]. Available from:

https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/zofran_inj.pdf

[Internet]. Medicines.org.uk. 2019 [cited 18 September 2019]. Available from:

https://www.medicines.org.uk/emc/files/pil.8482.pdf

[Internet]. Medicines.org.uk. 2019 [cited 18 September 2019]. Available from:

https://www.medicines.org.uk/emc/files/pil.6049.pdf
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Information on this page was last updated on 24 Sep 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.