Ondansetron

Description

Ondansetron is an antiemetic agent used to treat nausea and vomiting caused due to certain medical conditions. It is also used to treat nausea and vomiting caused by cancer chemotherapy and radiation therapy. It works by blocking the action of a chemical substance that causes nausea and vomiting. The most common side effects are constipation and headache.

Side effects

Major & minor side effects for Ondansetron

  • Headache
  • Constipation
  • Fatigue
  • Painful urination
  • Fever
  • Dry mouth
  • Anxiety

Uses of Ondansetron

What is it prescribed for?

  • Nausea and vomiting
  • Chemotherapy induced nausea and vomiting
  • Post operative nausea and vomiting
Read More
Concerns

Commonly asked questions

  • Onset of action
    The peak effect of Ondansetron can be observed within 30 minutes for Intravenous and 2 hours for the tablet.
  • Duration of effect
    This medicine is excreted primarily in urine and the effect of this medicine lasts for a duration of 12 to 28 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    Use of Ondansetron is not recommended in pregnant women.
  • Usage while breast-feeding?
    No clear data is available whether Ondansetron is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.

Allergy

Avoid if the patient has a known allergy to Ondansetron.

Apomorphine

Avoid using Ondansetron with Ondansetron as it increases the risk of lightheadedness and loss of consciousness.
Warnings for special population

Pregnancy

Use of Ondansetron is not recommended in pregnant women.

Breast-feeding

No clear data is available whether Ondansetron is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.
General warnings

Hypersentivity

Avoid if the patient has a known allergy to Ondansetron.

Liver disease

Avoid using if the patient is having any liver disease as there are reports of Ondansetron increasing patient's liver enzymes.

Paediatics

Avoid using in children who are younger than 4 years.

Overdose

Seek emergency medical attention or contact the doctor in case of overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Carbamazepine

Phenytoin

Amiodarone

Apomorphine

Cyclophosphamide

Disease interactions

QT Prolongation

Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.

Liver Disease

Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Ondansetron with or without food. Do not take in larger amounts than advised. Consult the doctor if the patient experiences any undesirable effects.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
Ondansetron blocks the action of chemicals (serotonin) in the body that can trigger nausea and vomiting.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antiemetics

Schedule

OTC

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 2 Dec 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.