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Alrista SR Tablet
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Alrista SR Tablet

Manufactured byMACLEODS PHARMACEUTICALS PVT.LTD
ContainsEpalrestat
Description
Alrista SR Tablet is an aldose reductase inhibitor used for the treatment of diabetic peripheral neuropathy, one of the most common long-term complications in patients suffering from diabetes mellitus.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Alrista SR Tablet

Aldonil OD Tablet SR
Zydus Cadila

Side effects

Major & minor side effects for Alrista SR Tablet

  • Nausea and vomiting
  • Irregular heartbeat
  • Diarrhea
  • Abdominal pain
  • Dry mouth
  • Weakness and general discomfort
  • Chills
  • Dizziness
  • Headache
  • Rash

Uses of Alrista SR Tablet

What is it prescribed for?

  • Diabetic Peripheral Neuropathy
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to epalrestat or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Driving or operating machinery

This medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during treatment with this medicine.

Liver impairment

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by your doctor. You are advised to take this medicine before food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine reduces the levels of sorbitol which is responsible for damage to the nerves.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Aldose reductase inhibitor

Schedule

Schedule H

[Internet]. Pdfs.semanticscholar.org. 2018 [cited 9 April 2018]. Available from:

https://pdfs.semanticscholar.org/4759/1bb62346cee5cd9d69c40a67c68ca777ff1f.pdf

[Internet]. Pharmrev.aspetjournals.org. 2018 [cited 9 April 2018]. Available from:

http://pharmrev.aspetjournals.org/content/pharmrev/64/4/880.full.pdf

NL R. Epalrestat: an aldose reductase inhibitor for the treatment of diabetic neuropathy. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 9 April 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/18447661

Epalrestat [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 17 June 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Epalrestat
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Information on this page was last updated on 18 Jun 2020

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