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Pregabalin and duloxetine
Hello, my Age is 60. I was diagnosed with lateral canal stenosis at L4-L5 and was prescribed Neurokem D 75/20 (pregabalin duloxetine). I took my first dose last night.After taking it, I had severe shivering, felt extremely cold, became confused in morning (as noticed by my family), and I'm still very sleepy even now when its 4 pm. I also feel bloated or like I've suddenly gained weight.Should I continue this medicine or stop it? Please guide me on this. I am really confused how to cure my back pain permanently.
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Answers (1)

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Care AI Shimmer
Hello. GI issues  like bloating are expected with duloxetine, so it is advised to take PPI tablet like pantop 40 mg initially for a week till you are accustomed to the new medication. pregabalin can cause drowsiness, giddiness - so one way to reduce that is to take it by 6-7pm in the evening. Donot change your position from lying down to sitting or standing immediately - wait for 2-3 min in one postion before changing. If your body is still not tolerating this medication in 2-3 days, visit your doctor locally and they will consider reducing the dose or  make dulox 20 mg in the morning  after breakfast and pregabalin 75ug  at night 7pm. For back pain relief - it needs detailed examination and opinion - so please visit neuromedicine/surgery for further treatment
Next Steps
take the tablet early by 6-7pm with gastric  medication like pantop 40 mg before breakfast  in the morning. wait for 2-3 days - if still all issues persist - visit you doctor
Health Tips
giddiness is expected - so don't chang tour postion fastly
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.