Is mesotherapy effective? Long term?

I've had hairfall issue since 1 year i consulted with a dermat and found out that i had low vitamin d and b12 so she prescribed me b12 and d suppliments for 3 months and biotin suppliment and mintop 5% for almost an year with a little gap in between. it has definitely reduced the hair fall but i still am not happy with my hair as they still look really thin and I don't want to continue mintop and biotin as i feel they are causing dryness and frizz in hair and acne issues on my face . my dermat had mentioned mesotherapy and said it would be really good and when i researched i felt prp might be better but i was concerned that even after doing them the suppliments are being prescribed so is there any other better treatment which wouldn't require suppliments and would be effective long term?