Feeling like looser. Thought of meetin!

Hi, I was very active and felt very successful but last two and now I very like am looser, peoples around do not like me, they don't want talk to me or am struggling to make conversation with them. Even in my carrier my review is to talk and mingle a lot. Things are happening like everyone wants to ignore me. If anything goes wrong, people tells me that am the reason for but I am damn sure am not. My client appreciate my work, but talks lot to other team members not me and am getting instructions or informations from them. My wife is stressful because of carrier and her father, I have taken so personally of her all stress in my head and tried to resolve it too, but people keep telling me that am reason for her stress by only seeing me and not knowing what's happening at background. I always gets feeling to run away from everything or go somewhere, where I can be lonely or around the people who loves or care me. I do know what's the problem happening to me, that's I thought of meetin