Anxiety, Fear, Depression. And advise.

My friend used be very confident and fearless during college time but for last three years she has been suffering from a strange mental state where she feels anxiety, fear, sometimes depression, mood swings, irritation, anger. This is a continuous thought/feeling and not dependent on any day or situation. She is afraid leaving house and parents, afraid of living alone, feels nausea all the time. Consulted a couple of Docs and they suggested anti-depression pills like nexito. She is an engineer by profession and wants to have a good career but this continuous feeling prevents her going anywhere. She has tried keeping herself busy in many things like teaching and hobbies but nothing helped. Smoking - No Drinking - No Any trauma - No Please suggest and advise.