It is very painful to feel negative about your self all the time . Lot of people feel that way about themselves at some point in their life . We diagnose depression when this feeling of worthlessness or hopelessness continues for more than 2 weeks along with sleep, appetite problems, lose of interest in pleasurable activities, decrease activity , sad mood or suicidal thoughts etc , Yes there are lot of options both medication and therapy Detailed evaluation is required for definitive conclusion