I have been taking venlafaxine 75 mg for around 6 years for depression. Over the years, I have gradually experienced reduced sexual desire, arousal and erection quality. Initially, normal sexual content could stimulate me, but gradually I needed stronger stimulation to feel excited or achieve an erection. Recently, even extreme sexual content does not produce much excitement or erection. I can sometimes achieve an erection and orgasm with intense stimulation. I previously had a penile ultrasound and physical examination, and both were normal; the andrologist did not suspect a vascular problem. I also stopped venlafaxine for 90 days under medical supervision, but my sexual function did not improve, while my depression returned.