Deviry (medroxyprogesterone) 10 mg for 10 days is not
liver-toxic and is generally safe to withdraw a period in PCOS - but your SGPT 165 and SGOT 97 are 4-5 times normal and that is the real problem here, not the Deviry. With a weight of 110-115 kg at 5'6",
HbA1c 6.0, PPBS 137,
triglycerides 153 and PCOS on ultrasound, this picture is fatty liver disease (NAFLD) with prediabetes and insulin resistance, and BP 140/80 needs watching too. Before starting anything, get an ultrasound abdomen for fatty liver, hepatitis B and C screening, and repeat
LFT - alcohol, painkillers and any herbal or weight-loss supplements must stop completely. Real treatment is 7-10 percent weight loss with diet and daily exercise, often metformin, and progesterone or combined pills for cycle regulation once the liver is assessed.
Next Steps
Get ultrasound abdomen, hepatitis B and C screening and a repeat
LFT, and take Deviry only under your gynaecologist's supervision. Book a consult with me on Practo or at Synergy Multispeciality Hospital, Miraj with all reports so the fatty
liver, prediabetes and blood pressure are treated together.