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Your SGPT (ALT) 131 and SGOT (AST) 65 are elevated (approximately 2–3 times the upper limit of normal). This indicates mild to moderate transaminitis and requires evaluation, but it is not an emergency if you are asymptomatic. Since you are on TLD for 8 years,medication-related liver enzyme elevation is possible, but after long-term stable therapy, other causes must also be ruled out. Common causes to consider: Drug-induced liver injury Fatty liver disease (very common at this age) Hepatitis B or C co-infection Alcohol intake Important: Do not stop ART on your own.

Most probably it's due to TLD medicine Investigation - Hepatitis profile

Due to meds

*Get your CD4 count checked along with Hep A, B , C , D, E tests *EBV IgM&IgG *CMV IgM&IgG *Lipid profile *CBP, TSH, Ferritin Ultrasound abdomen Have LFT tested every week for four weeks to see if it settling. They usually do. All the best. WWW.JGSR-HEALTH-EDUCATION.IN

Liver enzymes are high,  can be due to tab TLD or some other cause, get tests done for hepatitis B and C, ultrasound abdomen done and share results.

Your SGPT (131) and SGOT (65) are elevated. SGPT is about 3–4 times normal, so it is moderately high. Possible causes: • ART medicines (TLD can sometimes affect liver) • Fatty liver • Alcohol intake • Viral hepatitis (B or C) • Other medicines or supplements What to do: • Do not stop ART on your own • Repeat LFT after 2–4 weeks • Check Hepatitis B & C status if not done • Avoid alcohol and unnecessary medicines • Do ultrasound abdomen If values keep increasing or you have jaundice, vomiting, or severe weakness, see your doctor urgently. Based on your symptoms, this may require proper clinical assessment and prescription. You may book an online consultation with me for detailed evaluation and personalised treatment plan.

Can help you, kindly consult and provide detailed history for proper diagnosis and further management

Your values: • Serum GPT (ALT) = 131 • Serum GOT (AST) = 65 Normal range (lab dependent, approx): • ALT: up to ~40 • AST: up to ~40 So yes — ALT is about 3× upper limit, AST mildly elevated. This is a moderate liver enzyme elevation, not an emergency, but not normal either. You are on TLD (Tenofovir + Lamivudine + Dolutegravir) for 8 years. Possible causes: 1️⃣ ART-related liver enzyme elevation (can occur, though less common after long stable use) 2️⃣ Fatty liver (very common) 3️⃣ Alcohol intake 4️⃣ Viral hepatitis (HBV, HCV) 5️⃣ Recent infection 6️⃣ Gym supplements / herbal meds 7️⃣ Muscle injury (AST can rise with muscle strain) Important: If bilirubin is normal and you have no jaundice, it is usually not acute liver failure.

Please consult with your physician locally .

Consult superspecialist like liver specialist.

Serum GPT (ALT) 131 and Serum GOT (AST) 65 are elevated above normal limits. ALT is approximately 3 times the upper normal limit, indicating mild to moderate liver inflammation. This can be due to several causes such as antiretroviral therapy (TLD), fatty liver, alcohol intake, viral hepatitis (HBV/HCV), or other medications. Since you are on ART for 8 years, drug-related liver enzyme elevation is possible but needs proper evaluation before making any changes. It is not dangerously high at present but should not be ignored.

Please consult

Dear Patient, Your liver enzymes • SGPT (ALT) = 131 → Moderately elevated • SGOT (AST) = 65 → Mildly elevated possible causes include: • Drug-related liver enzyme elevation • Fatty liver • Alcohol intake (if any) • Viral hepatitis (A, B, C) • Recent infection or illness Advice • Repeat LFT after 2–3 weeks • Get Ultrasound abdomen • Test for Hepatitis B & C if not done recently • Avoid alcohol completely • Avoid unnecessary medicines/supplements Do NOT stop ART on your own. If enzymes rise above 3 times normal or you develop: • Yellow eyes • Severe weakness • Abdominal pain Seek urgent medical review. Kindly consult me on Practo with full reports for detailed evaluation and proper management plan.

Get usg done and have a follow up

Few more details needed for further evaluation. Kindly consult

Mostly due TLD medicine

Avoid fried and spicy food Water intake more Green leafy vegetables more Fiber meal Do connect and consult

Need a few more details please consult for further evaluation and treatment

Need some more details kindly consult