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Opinion: The swelling around both ankles that extends up to the knees, along with non-pitting edema (fluid retention), which comes and goes but has become more prominent and painful in the last two weeks, is concerning. The fact that your test results for kidney, heart, liver, and blood were normal does not rule out all possible causes. Some potential reasons for your persistent swelling and edema could include: 1. Venous insufficiency: Impaired blood flow in the veins of the legs, which can lead to fluid accumulation and swelling. 2. Lymphedema: Impaired lymphatic drainage, which can cause fluid buildup and swelling in the affected limbs. 3. Hormonal imbalances: Conditions like premenstrual syndrome (PMS) or hormonal contraceptive use can sometimes contribute to fluid retention and swelling. 4. Nutritional deficiencies: Deficiencies in certain nutrients, such as protein or vitamins, can lead to fluid retention and edema. 5. Autoimmune disorders: Some autoimmune conditions, like rheumatoid arthritis or lupus, can cause joint swelling and edema. Your elevated platelet count (480) may or may not be related to the swelling, but it's worth exploring further. Next Steps: 1. Consult with a vascular specialist or a rheumatologist for a more comprehensive evaluation. They may order additional tests, such as a Doppler ultrasound of the legs or specific blood tests, to identify the underlying cause. 2. Consider compression stockings or other compression devices, which can help improve blood flow and reduce swelling. 3. Elevate your legs whenever possible to promote drainage and reduce fluid buildup. 4. Maintain a well-balanced diet rich in protein, vitamins, and minerals to support overall health and prevent nutritional deficiencies. 5. Discuss with your physician the possibility of trying diuretic medications (with caution) or other medications that may help manage the swelling and edema more effectively. 6. Explore potential underlying causes, such as hormonal imbalances or autoimmune disorders, which may require specific treatment approaches. While the temporary use of diuretics like Dytor can provide relief, identifying and addressing the root cause of the swelling and edema is crucial for long-term management and preventing potential complications. A multidisciplinary approach involving specialists may be necessary to determine the most appropriate permanent treatment plan.

Patient's detailed medical history is required. It is recommended to consult a doctor professional through the Practo app or visit a local medical facility for a thorough evaluation. Please keep in mind that detailed medical history is crucial for proper diagnosis and treatment.

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