You need to understand that the creams which are available over the counter without prescription are so easily available because you do not have the right amount of active ingredients needed for proper treatment and that is why they do not fall under the purview of the drug control Organisation. The severity of acne dictates the choice of treatment. In the early grades of acne even the cream might suffice however in moderate to higher grades tablets also need to be taken. The treatment has to be continued for a few months otherwise the pimples would tend to return easily. Kindly do not self medicate without professional advice as that could further damage your skin. Get an online consult or meet a dermatologist directly for a proper evaluation of the condition. Hope this was helpful.