As the Extraction was done years back , it may not be cause of the discomfort. Discomfort may be due to various reasons
1) Malocclusion : As you mentioned your adjacent teeth has tilted to fill the extracted space, you must have a problem of Malocclusion where the upper and the lower teeth are not contacting each other properly or in the correct fashion and this may lead to increased stress on your lower two teeth which may result in discomfort or pain
2) Carious Teeth : The adjacent teeth may be carious and it should be diagnosed with radiographs
3) Periodontal issues
Next Steps
Consult a Dentist and Explain him/her about the issue you are facing.