Congenital hypoplasia of depressor anguli oris muscle The frequency of hypoplasia of the depressor anguli oris muscle was 37 cases among 4 530 consecutive births (8·2%). Diagnosis was based on clinical and electromyographic studies. Severe congenital anomalies were detected in 3 of the 37 cases, while another 3 newborns had minor congenital defects. In 17 of the 37 cases there were first- or second-degree relatives with lower lip asymmetry. A minimum of 13 out of the 74 parents of the probands were affected. The high incidence of affection among first-degree relatives of the probands is strong evidence of hereditary factors playing a role in the aetiology of this anomaly.

It can be genetic but not necessarily inherited. It can be sporadic or genetic change could be affecting few body cells . Consult your paediatrician for detailed examination.

Greetings presentation shares characteristics with an isolated finding, which can sometimes occur randomly without an underlying genetic pattern. However, it is also consistent with a syndromic condition, such as Cayler cardiofacial syndrome or a 22q11.2 microdeletion, where asymmetric facial expressions are paired with musculoskeletal or limb anomalies. Since your initial internal scans and echocardiogram are completely normal, the likelihood of a major systemic syndrome is lower. To explore this further, potential management options include seeking a formal clinical evaluation from a pediatric geneticist, pursuing targeted genetic testing (such as a chromosomal microarray), or consulting a pediatrician

I need to ask few more questions before answering your query. Kindly contact me on whatsapp chat  (84960595 six five) Dr Faisal Zoheb MBBS , MD PAEDIATRICS , PGPN (BOSTON), FELLOWSHIP IN NEONATOLOGY ( Newborn and vaccination specialist )

Yes it a genetic only

Visit physically to nearby pediatrician physically

A genetic cause is possible, but this does not necessarily mean it is inherited. It may also be a sporadic/de-novo abnormality, especially with no family history.