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Zygem 200 MG Injection
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Zygem 200 MG Injection

Manufactured byZydus Cadila
ContainsGemcitabine
Description
Zygem 200 MG Injection is an anticancer agent which is used in the treatment of cancer of pancreas, breast, lungs and ovaries. It should be used under the supervision of a qualified physician. Close monitoring of lung function and blood cell count are necessary while receiving this medication.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Zygem 200 MG Injection

Celgem 200 MG Injection
Alkem Laboratories Ltd.
Gemacta 200 MG Injection
Macleods Pharmaceuticals Pvt. Ltd.
Gemtrust 200 MG Injection
Panacea Biotec Ltd.
Oncogem 200 MG Injection
Cipla Ltd.
Xtroz 200 MG Injection
Ranbaxy Laboratories Ltd.

Side effects

Major & minor side effects for Zygem 200 MG Injection

  • Low WBC and Platelet count
  • Pale skin
  • Fever
  • Nausea and Vomiting
  • Diarrhea
  • Weakness of arms, hands, legs or feet
  • Headache
  • Hair loss or thinning of the hair
  • Drowsiness
  • Skin rash
  • Swelling and redness at the injection site

Uses of Zygem 200 MG Injection

What is it prescribed for?

  • Pancreatic Cancer
  • Non-Small Cell Lung Cancer
  • Breast cancer
  • Ovarian Cancer
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The peak effect of this medicine can be observed immediately after intravenous injection.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 2 to 5 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for pregnant women.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended in breastfeeding women.

Allergy

Not recommended in patients with known allergy to Zygem 200 MG Injection
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women.

Breast-feeding

This medicine is not recommended in breastfeeding women.
General warnings

Liver injury

This medicine may cause liver injury and causes death. The liver function parameters need to be assessed before starting the treatment. The treatment should be discontinued if any signs and symptoms of liver injury appear.

Kidney injury

This medicine may cause Hemolytic Uremic Syndrome (HUS) which is a serious condition that causes fatalities. The kidney function parameters need to be assessed before starting the treatment. The treatment should be discontinued if any signs and symptoms of kidney injury appear.

Lung toxicity

This medicine may cause severe lung injuries like pulmonary fibrosis, pulmonary interstitial infiltrates. Any symptoms of breathing difficulty and signs of lung impairment should be informed to the doctor. The treatment should be discontinued if any symptoms appear.

Decrease in blood cell count

This medicine may lower the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell count is necessary. The baseline of the blood cell count should be obtained before initiation of the treatment. Do not start the treatment if the counts are less.

Infections

The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

Missed Dose

It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clozapine

Warfarin

Live vaccines

Fluoroquinolone antibiotics

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and lung function is necessary.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It interferes with DNA synthesis and prevents its growth.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antimetabolites

Schedule

Schedule H

[Internet]. 2017 [cited 10 May 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/33137

Gemcitabine Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a696019.html

DailyMed - Gemcitabine hydrochloride injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 10 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d16907e7-a8c8-4039-ace4-cf4e24ba68c0

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 10 May 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname
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Information on this page was last updated on 8 Jan 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.