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Zonegran 100 mg Tablet
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Zonegran 100 mg Tablet

Manufactured byEisai Pharmaceuticals India Ltd.
ContainsZonisamide
Description
Zonegran 100 mg Tablet is an anticonvulsant medicine, used for the treatment of certain types of seizures (partial seizures). This medicine is not recommended for use in patients under 16 years of age. This medicine should be used with extreme caution in patients suffering from liver diseases and depression.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Zonegran 100 mg Tablet

  • Irritability
  • Mood or mental changes
  • Trouble with sleeping
  • Loss of appetite
  • Shakiness or unsteady walking
  • Easy bruising and bleeding
  • Rash

Uses of Zonegran 100 mg Tablet

What is it prescribed for?

  • Partial onset seizures
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time taken by this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use of you are known allergic to zonisamide or any other inactive ingredients present in the formulation.

Sever liver impairment

This medicine is not recommended for use in patients with active liver disease due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Skin reactions

This medicine may cause severe skin reactions like stevens-johnson syndrome and toxic epidermal necrolysis. Inform the doctor if any symptoms appear and discontinue the treatment as early as possible.

Effect on blood

This medicine is not recommended for use in patients with a known history of blood disorders. Close monitoring of CBC and platelet levels are recommended while receiving this medicine.

Suicidal tendency

This medicine may cause suicidal behavior in some patients. This risk is especially higher on the prolonged usage of the medicine. Patients should be monitored closely for any changes in behavior and mood; any such changes should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Withdrawal symptoms

This medicine may cause withdrawal symptoms if the usage is stopped abruptly. This risk is especially higher after prolonged usage of this medicine. The treatment should be withdrawn gradually under the close supervision of your doctor. Do not stop the use of this medicine without consulting your doctor.

Driving or operating machinery

The use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in children

This medicine is not recommended for use in patients less than 16 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any undesirable side effects.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
Interaction with Medicine

Amitriptyline

Erythromycin

Ketoconazole

Alprazolam

Dicyclomine

Disease interactions

Depression

This medicine is not recommended for use in patients with a known history of depression due to an increase in the risk of worsening depression, suicidal thoughts, and unusual mood changes. Monitor the patients closely for any worsening of symptoms. Consult your doctor immediately if you notice any behavioural changes.

Bone Marrow Depression/Blood Dyscrasias

This medicine is not recommended for use in patients with a known history of blood disorders due to an increase in the risk of bone marrow depression and anemia. Close monitoring of CBC and platelet count is recommended while receiving this medicine.

Kidney disease

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by the doctor. Drink plenty of fluids during treatment with this medicine to reduce the risk of kidney stone formation. Do not take this medicine in larger amounts than advised. Consult the doctor immediately if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by decreasing the abnormal electrical activity in the brain, thus stopping the seizure activity.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Anticonvulsants

Schedule

Schedule H

Zonisamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 28 April 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a603008.html

Zonisamide - DrugBank [Internet]. Drugbank.ca. 2020 [cited 28 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB00909

Zonisamide [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 29 April 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Zonisamide

Search results detail| Kusurino-Shiori(Drug information Sheet) [Internet]. Rad-ar.or.jp. 2020 [cited 29 May 2020]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=33681
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Information on this page was last updated on 29 May 2020

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