Ziprasidone

Description

Ziprasidone is used for the treatment of schizophrenia and mania associated with bipolar disorder. It is not recommended for use in elderly patients with dementia-related psychosis due to the increased risk of death.

Side effects

Major & minor side effects for Ziprasidone

  • Cough
  • Fever
  • Sore throat
  • Sneezing
  • Restlessness
  • Blurred vision
  • Congestion
  • Chest pain
  • Headache

Uses of Ziprasidone

What is it prescribed for?

  • Schizophrenia
  • Bipolar I disorder
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, and impaired judgment. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ziprasidone.

Myocardial infarction

Ziprasidone is not recommended for use in patients with a history of recent myocardial infarction due to the increased risk of worsening of the patient's condition.

Prolonged QT interval

Ziprasidone is not recommended for use in patients with a known history of prolonged QT interval due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Hypotension

This medicine should be used with caution in patients with a history of hypotension due to the increased risk of worsening of the patient's condition.

Hyperglycemia

This medicine should be used with caution in patients with a history of hyperglycemia due to the increased risk of very high blood glucose levels.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, and impaired judgment. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amlodipine

Clozapine

Erythromycin

Amiodarone

Ciprofloxacin

Doxorubicin

Disease interactions

Seizures

This medicine should be used with caution in patients with a known history of seizures due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes due to the increased risk of elevated blood glucose levels. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Ziprasidone with food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Ziprasidone acts on certain natural chemicals in the brain to bring about a change in patient's behavior and thinking.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 18 August 2017]. Available from:

http://www.tga.gov.au/prescribing-medicines-pregnancy-database

TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 18 August 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2

Ziprasidone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00246

Ziprasidone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a699062.html

DailyMed - ZIPRASIDONE- ziprasidone hydrochloride capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=315e24c2-2f8c-47d9-b1b1-ce006646098a

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Information on this page was last updated on 4 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.