Zileuton

Description

Zileuton is an effective medicine used to prevent and treat asthma in adults and children 12 years of age and older. It prevents the action of certain chemicals in the body that causes allergic reactions.

Side effects

Major & minor side effects for Zileuton

  • Cough
  • Headache
  • Nausea and Vomiting
  • Stuffy nose
  • Stomach upset
  • Diarrhea
  • Sore throat

Uses of Zileuton

What is it prescribed for?

  • Asthma
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed after 2-5 hours of administration.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Zileuton or any other inactive ingredient present along with it.

Liver Disease

This medicine is not recommended for use in patients with liver diseases due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Use in Children

This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established.

Behaviour and mood changes

This medicine can cause changes in behavior and mood. Symptoms like agitation, irritability, anxiety, unusual dreams, suicidal thoughts should be reported to the doctor. Caution is advised while giving this medicine to people with pre-existing psychiatric disorders.

Missed Dose

Take the missed dose as soon as you remember. The missed dose should be skipped if it is almost time for the next scheduled dose.

Overdose

Seek emergency medical atreatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Leflunomide

Teriflunomide

Rasagiline

Aminophylline

Disease interactions

Liver Disease

This medicine is not recommended for use in patients with liver diseases due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative might be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by your doctor. Follow all the instructions given in the information leaflet. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
This medicine acts by blocking the response of certain specific chemicals that cause allergic responses in the body.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Leukotriene modifiers

Schedule

Schedule H

Zileuton [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 12 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/60490#section=Pharmacology-and-Biochemistry

DailyMed - Zileuton- zileuton tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 12 December 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=eac21801-4b9b-41bc-a37d-e30d43639d5e

[Internet]. Accessdata.fda.gov. 2018 [cited 12 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020471s017lbl.pdf

Zileuton - DrugBank [Internet]. Drugbank.ca. 2019 [cited 21 February 2019]. Available from:

https://www.drugbank.ca/drugs/DB00744

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Information on this page was last updated on 22 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.