Zafirlukast

Description

Zafirlukast is an effective medicine used to prevent and treat allergic conditions such as asthma. This medicine should not be used to treat a sudden attack of asthma symptoms. It does not cure asthma but controls the symptoms of asthma.

Side effects

Major & minor side effects for Zafirlukast

  • Cough or hoarseness
  • Difficult or painful urination
  • Lower back or side pain
  • Fever or chills
  • Dark urine
  • Diarrhea
  • Headache
  • Itching
  • Loss of appetite
  • Nausea
  • Rash

Uses of Zafirlukast

What is it prescribed for?

  • Asthma
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required by this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to zafirlukast or any other components present along with it.

Status asthmaticus

This medicine is not recommended for use in patients with status asthmaticus, a severe and acute attack of asthma.

Hepatic impairment

This medicine is not recommended for use in patients with a known history of hepatic impairment due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Acute Bronchospasm

This medicine is not recommended for use in patients with an acute bronchospasm since it is slow acting.

Acute asthma attacks

This medicine is not recommended for use in patients with acute asthma attacks since it is slow acting.

Warfarin

This medicine should be used with caution in patients taking warfarin due to the increased risk of excessive bleeding. Any symptoms such as unusual bleeding or bruising, headache, blood in urine or stools, weakness, etc. should be reported to the doctor immediately.

Hepatic dysfunction

This medicine is not recommended for use in patients with a known history of hepatic impairment due to the increased risk of serious adverse effects.

Use in children

This medicine is not recommended for use in children less than 5 years of age since the safety and efficacy of use are not clinically established.

Use in Geriatrics

This medicine should be used with caution in patients greater than 65 years of age due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. The missed dose should be skipped if it is almost time for the next scheduled dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amiodarone

Leflunomide

Aspirin

Dapsone

Atorvastatin

Fentanyl

Disease interactions

Liver Disease

This medicine is not indicated for use in patients with a known history of liver impairment including liver cirrhosis due to the increased risk of serious adverse effects.
Food interactions
Food may reduce the absorption of Zafirlukast. It is advised to take this medicine on an empty stomach, at least 1 hour before a meal or 2 hours after a meal.
Lab interactions
Information not available.
Take Zafirlukast as instructed by the doctor. Follow all the instructions mentioned on the label or package insert. This medicine should be taken on an empty stomach, at least 1 hour before a meal or 2 hours after a meal. Do not take in larger or smaller quantities than prescribed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine acts by blocking the response of certain specific chemicals that cause allergic responses in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Leukotriene modifiers

Schedule

N/A

DailyMed: Zafirlukast tablet, coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 29 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0262e192-94f4-423d-a58e-bb374dc106fe

EMC [Internet]. 2017 [cited 29 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/2269

Toxnet [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 29 August 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~iJRyf1:1

Zafirlukast - DrugBank [Internet]. Drugbank.ca. 2017 [cited 29 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00549

Zafirlukast: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 29 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a697007.html

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 15 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.