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Xexto MR Tablet
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Xexto MR Tablet

Manufactured byGufic Bioscience Ltd.
ContainsAceclofenac (100 mg) + Paracetamol (500 mg) + Chlorzoxazone (250 mg)
Description
Xexto MR Tablet is a combination of Aceclofenac, Paracetamol and Chlorzoxazone. It is used for the treatment of pain, swelling, and tenderness associated with muscle injury and muscle spasms. This medicine works by blocking the release of certain chemical messengers that cause pain and swelling. Xexto MR Tablet shows side effects like nausea, vomiting, stomach pain, heartburn, diarrhoea and tiredness. This medicine may cause dizziness or sleepiness. Hence, avoid driving vehicles or operating machines. Xexto MR Tablet should be taken with food to avoid stomach irritation. Adhere to the dose and frequency prescribed by your doctor. You should keep taking the medicine even if you feel better until your doctor says to stop using it. Avoid consuming alcohol while taking Xexto MR Tablet as it may cause excessive drowsiness and also increase the risk of liver damage. Xexto MR Tablet may interact with other medicines and health conditions. Inform your doctor if you have liver, heart, or kidney problems and/or stomach ulcers before taking Xexto MR Tablet. Also, inform your doctor about all the other medicines you are using. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Xexto MR Tablet

  • Dizziness
  • Drowsiness
  • Nausea and Vomiting
  • Dark urine
  • Bloody stool
  • Tiredness
  • Weakness
  • Stomach pain
  • Tightness of chest
  • Constipation
  • Diarrhoea
  • Skin rash
  • Heartburn

Uses of Xexto MR Tablet

What is it prescribed for?

  • Pain due to muscle spasm
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The pain-relieving effect of Xexto MR Tablet can be observed within an hour.
  • How long do the effects of this medicine last?
    Xexto MR Tablet remains active in the body for up to 12-16 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol while taking Xexto MR Tablet. It may increase the risk of side effects such as dizziness, headache, gastrointestinal bleeding, weakness, fatigue, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Xexto MR Tablet.
  • Can this medicine be taken during pregnancy?
    Xexto MR Tablet is not recommended for use during pregnancy due to the risk of harmful effects to your foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    It is not known if Xexto MR Tablet passes into the breastmilk or not. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Xexto MR Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Kidney Disease

Xexto MR Tablet may impair your kidney function and lead to its damage. Hence, it is not recommended if you have medical conditions that severely affect your kidneys.

Severe liver impairment

Patients with liver problems need special consideration while taking Xexto MR Tablet.The use of this medicine is generally not recommended in such cases because it can increase the risk of liver damage. Hence, consult your doctor before taking this medicine.

Gastro-intestinal bleeding

Xexto MR Tablet is not recommended if you have stomach and intestinal bleeding. The use of this medicine may worsen your condition.

Peptic Ulcer

Avoid taking Xexto MR Tablet if you have ulcers in the stomach and intestine. This medicine can cause severe swelling and bleeding in the stomach, colon, and anus. Hence, it may worsen your condition.

Bleeding disorder

Xexto MR Tablet may prolong the blood clotting time and therefore increase the risk of bleeding. Hence avoid using this medicine if you have a bleeding disorder as it may worsen your condition.
Warnings for special population

Pregnancy

Xexto MR Tablet is not recommended for use during pregnancy due to the risk of harmful effects to your foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

It is not known if Xexto MR Tablet passes into the breastmilk or not. Hence, consult your doctor if you are breastfeeding.
General warnings

Chronic Malnutrition

Malnutrition is a deficiency or imbalance in your body's intake of nutrients and energy. Malnutrition can increase the risk of toxicity associated with taking Xexto MR Tablet. Dose adjustment may be necessary based on your body weight.

Gastro-intestinal toxicity

Take Xexto MR Tablet with caution as long term use can cause damage to the stomach and intestine. Serious conditions like ulcers and bleeding in the stomach and/or intestine may occur.

Driving or operating machines

Xexto MR Tablet may cause sleepiness or dizziness. Avoid driving vehicles and/or operating heavy machines after taking this medicine.

Missed Dose

Try not to skip the scheduled dose of Xexto MR Tablet. If you missed a dose, take it as soon as you remember. However, if it is time for the next dose, skip the dose. Never take a double dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Reach the nearest emergency medical department or contact your doctor in case of Xexto MR Tablet overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol while taking Xexto MR Tablet. It may increase the risk of side effects such as dizziness, headache, gastrointestinal bleeding, weakness, fatigue, etc.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Tramadol

Sodium Nitrite

Leflunomide

Prilocaine

Atenolol

Disease interactions

Liver Disease

Take Xexto MR Tablet with caution if you have liver problems as this medicine may lead to liver damage. Dose adjustments may be necessary.

Kidney Disease

Prolonged use of high doses of Xexto MR Tablet may cause kidney problems. Hence, close monitoring of kidney function is necessary.

Heart Disease

Xexto MR Tablet is not recommended if you have heart problems as it may worsen your condition. Consult your doctor before taking this medicine.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

Xexto MR Tablet can interfere with urine tests and may give a false-positive result. Inform your doctor and lab technician about all your current medicines before undergoing any lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Xexto MR Tablet with food to avoid stomach irritation. Drink adequate water for easy swallowing. Do not break, crush or chew the tablet in the mouth. Never take more than the prescribed dose. Take Xexto MR Tablet around the same time daily. Do not stop taking this medicine without consulting your doctor. Avoid consuming alcohol when taking Xexto MR Tablet as it may cause excessive drowsiness and also increase the risk of liver damage. Avoid taking Xexto MR Tablet with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. Keep the medicine out of reach of children and pets. Check the expiry date before taking Xexto MR Tablet.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Xexto MR Tablet is a combination of Aceclofenac, Paracetamol and Chlorzoxazone. Aceclofenac works by inhibiting the formation of certain chemical substances in the body that cause pain and swelling. Paracetamol helps in reducing the pain signals responsible for swelling and pain. Chlorzoxazone acts on the spinal cord and brain to reduce the impulses responsible for muscle spasms.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents, Skeletal muscle relaxants, Miscellaneous analgesics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Medicines.org.uk. 2021. Aceclofenac 100 mg film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 6 August 2021].

https://www.medicines.org.uk/emc/product/4240/smpc>

Dailymed.nlm.nih.gov. 2021. DailyMed - CHLORZOXAZONE tablet. [online] Available at: < [Accessed 14 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f05e8e2-616f-475b-ac9f-c42e1a5dbe81>
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Information on this page was last updated on 28 Oct 2021

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