Loading interface...

Wypal DS Tablet

Manufactured byJAGSONPAL PHARMACEUTICALS LTD
ContainsTrimethoprim (160 mg) + Sulfamethoxazole (800 mg)
Description

Wypal DS Tablet is used to treat susceptible infections caused by gram-negative and gram-positive bacterias, including Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus ducreyi, Nocardia, Streptococcus faecalis, E.coli, Pneumocystis jiroveci, Haemophilus influenzae, Klebsiella granulomatis, etc. It is also used to treat and prevent toxoplasmosis.

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now

Side effects

Major & minor side effects for Wypal DS Tablet

  • Stomach upset
  • Nausea and Vomiting
  • Diarrhea
  • Itching and skin rash
  • Black or tarry stools
  • Headache
  • Shortness of breath
  • Unusual bleeding or bruising
  • Yellow eyes or skin

Uses of Wypal DS Tablet

What is it prescribed for?

  • Pneumocystis Jiroveci Pneumonia
  • Toxoplasmosis
  • Nocardiosis
  • Acute uncomplicated urinary tract infection (UTI)
  • Acute exacerbations of chronic bronchitis
  • Acute otitis media
  • Traveler's Diarrhea
  • Granuloma inguinale
  • Chancroid
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid alcohol intake during treatment with this medicine due to the risk of side effects such as fast heartbeats, tingly feeling, warmth or redness under your skin, nausea, vomiting, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to trimethoprim, sulfamethoxazole, or any other inactive ingredients present along with the formulation.

Porphyria

This medicine is not recommended for use in patients with a known history of porphyria (a disorder that results from the accumulation of porphyrins in the body) due to an increase in the risk of worsening of the patient's condition.

Severe liver/kidney damage

This medicine is not recommended for use in patients with severe liver or kidney impairment since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Liver impairment

This medicine should be used with extreme caution in patients with liver impairment due to the risk of worsening of the patient's condition. Close monitoring of liver function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug-resistant.

Clostridium difficile-associated diarrhea

Discontinue the use of this medicine as per the doctor's instructions if severe diarrhea occurs after receiving this medicine. This medicine may cause an imbalance in the microbial flora of the large intestine, decreasing the gut-friendly bacteria and promoting the growth of a bacteria called Clostridium difficile, resulting in severe diarrhea.

Folate deficiency

Use of this medicine may cause folate deficiency in some patients and hence it is advised to take folic acid supplements along with this medicine. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Hyperkalaemia

This medicine may increase the blood potassium levels in some patients. Close monitoring of blood potassium levels is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

G6PD deficiency

This medicine should be used with extreme caution in patients with G6PD deficiency due to the risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Use in children

This medicine is not recommended for use in children below 12 years of age since the safety and efficacy of use are not clinically established.

Crystalluria

Use of this medicine may cause crystalluria due to the precipitation of this medicine in the urinary tract. This risk is especially higher in patients suffering from dehydration. Patients are advised to drink an adequate amount of water during treatment with this medicine. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hypersensitivity reactions

This medicine should be used with caution in patients with severe allergies, bronchial asthma, or AIDS due to the increased risk of severe hypersensitivity reactions. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid alcohol intake during treatment with this medicine due to the risk of side effects such as fast heartbeats, tingly feeling, warmth or redness under your skin, nausea, vomiting, etc.
Interaction with Medicine

Angiotensin Receptor Blockers (ARB)

Phenytoin

Methotrexate

Estradiol

Warfarin

Metformin

Disease interactions

Folate deficiency

This medicine is not recommended for use in patients with megaloblastic anemia caused by folate deficiency due to the risk of worsening of the patient's condition. It should be used with extreme caution in patients with malabsorption syndrome and who are on other folate depleting medications. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Renal Disease

This medicine should be used with extreme caution in patients with mild to moderate kidney impairment due to the risk of worsening of the patient's condition. Close monitoring of kidney function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Hematologic Toxicities

This medicine should be used with caution in patients with a known history of blood disorders or bone marrow disorders due to the increased risk of serious side effects. These side effects may include clotting disorders, methemoglobinemia, thrombocytopenia, aplastic anemia, or hemolytic anemia. Report any symptoms such as fever, sore throat, bleeding, or pale skin to the doctor on priority. Close monitoring of blood cell counts may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Complete the course of treatment to prevent the spread of the infection. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine prevents the growth of the bacteria by inhibiting certain steps in the biosynthesis of purines and therefore nucleic acids which is necessary for DNA replication.
Legal Status

Unknown

Approved

Approved

Approved

Classification

Category

Antibiotics, Sulfonamides

Schedule

Schedule H

Co-Trimoxazole 160 mg/800 mg Tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 15 May 2019]. Available from:

https://www.medicines.org.uk/emc/product/6997/pil

[Internet]. India-pharma.gsk.com. 2019 [cited 12 August 2019]. Available from:

http://india-pharma.gsk.com/media/701285/septran-and-sepmax.pdf

Trimethoprim - DrugBank [Internet]. Drugbank.ca. 2019 [cited 15 May 2019]. Available from:

https://www.drugbank.ca/drugs/DB00440

Sulfamethoxazole - DrugBank [Internet]. Drugbank.ca. 2019 [cited 15 May 2019]. Available from:

https://www.drugbank.ca/drugs/DB01015
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 12 Aug 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.