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Voritrop 200 MG Injection

Manufactured byIntas Pharmaceuticals Ltd.
ContainsVoriconazole
Description
Voritrop 200 MG Injection is used to treat a variety of serious life-threatening fungal infections of the lungs, mouth, and throat. It is not recommended for use in patients with a known allergy to it.

Side effects

Major & minor side effects for Voritrop 200 MG Injection

  • Increased sensitivity of the eyes to sunlight
  • Skin rash
  • Abdominal pain
  • Convulsions
  • Dizziness
  • Increased thirst
  • Yellow colored eyes or skin
  • Muscle pain
  • Irritability
  • Severe sunburn
  • Diarrhea
  • Headache
  • Pain at the injection site

Uses of Voritrop 200 MG Injection

What is it prescribed for?

  • Invasive Aspergillosis
  • Candidemia
  • Scedosporiosis
  • Fusariosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to voriconazole, or any other inactive ingredients present along with the formulation.

QT Interval prolonging drugs

This medicine is not recommended for co-administration with medicines that are known to cause specific changes in heart rhythm.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Visual disturbances

This medicine may cause visual disturbances like optic neuritis and papilledema. Close monitoring of visual function is necessary if treatment continues beyond 28 days.

QT prolongation

This medicine should be used with caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

Monitoring pancreas function

This medicine may increase the risk of pancreatitis in patients who have undergone recent chemotherapy or hematopoietic stem cell transplantation. Close monitoring of the functioning of the pancreas is necessary while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Skin reactions

This medicine may cause serious skin reactions like Stevens-Johnson syndrome or photosensitivity skin reaction. Close monitoring of skin reactions is necessary while receiving this medicine. Avoid exposure to sunlight by wearing protective clothing and using sunscreen with a high sun protection factor (SPF).

Use in children

The safety and effectiveness of this medicine are not established in patients who are less than 2 years of age.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Alprazolam

Cisapride

Clopidogrel

Warfarin

Atorvastatin

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart rhythm disorders

This medicine should be used with caution in patients having heart rhythm disorders. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by stopping the production of a certain vital component for the fungi. This results in the disruption of the cell membrane formation process and inhibits the growth of the organism.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Azole antifungals

Schedule

Schedule H

[Internet]. 2017 [cited 23 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/10059

Voriconazole - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB00582

Voritek Tablets/Injection [Internet]. CiplaMed. 2020 [cited 22 January 2020]. Available from:

https://www.ciplamed.com/content/voritek-tabletsinjection
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Information on this page was last updated on 28 Jan 2020

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