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Voraze 200 MG Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsVoriconazole
Description
Voraze 200 MG Tablet is used to treat a variety of fungal infections of the lungs, mouth, and throat, etc. Take this medicine at least 1 hour before or after food. Do not take this medicine if you have a known allergy to it.

Side effects

Major & minor side effects for Voraze 200 MG Tablet

  • Increased sensitivity of the eyes to sunlight
  • Skin rash
  • Abdominal pain
  • Convulsions
  • Dizziness
  • Increased thirst
  • Yellow colored eyes or skin
  • Muscle pain
  • Irritability
  • Severe sunburn
  • Diarrhea
  • Headache

Uses of Voraze 200 MG Tablet

What is it prescribed for?

  • Invasive Aspergillosis
  • Esophageal Candidiasis
  • Candidemia
  • Fungal Pneumonia
  • Fusariosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to voriconazole, or any other inactive ingredients present along with the formulation.

QT Interval prolonging drugs

This medicine is not recommended for co-administration with medicines that are known to cause specific changes in heart rhythm.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Visual disturbances

This medicine may cause visual disturbances like optic neuritis and papilledema. Close monitoring of visual function is necessary if treatment continues beyond 28 days. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience blurred vision or any visual disturbances.

QT prolongation

This medicine should be used with caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

Monitoring pancreas function

This medicine may increase the risk of pancreatitis in patients who have undergone recent chemotherapy or hematopoietic stem cell transplantation. Close monitoring of the functioning of the pancreas is necessary while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Skin reactions

This medicine may cause serious skin reactions like Stevens-Johnson syndrome or photosensitivity skin reaction. Close monitoring of skin reactions is necessary while receiving this medicine. Avoid exposure to sunlight by wearing protective clothing and using sunscreen with a high sun protection factor (SPF).

Use in children

The safety and effectiveness of this medicine are not established in patients who are less than 2 years of age.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Alprazolam

Cisapride

Clopidogrel

Warfarin

Atorvastatin

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart rhythm disorders

This medicine should be used with caution in patients having heart rhythm disorders. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
It is recommended to take this medicine at least 1 hour before or after food for better absorption.
Lab interactions
Information not available.
Take this medicine on an empty stomach at least 1 hour before or after food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by stopping the production of a certain vital component for the fungi. This results in the disruption of cell membrane formation process and inhibits the growth of the organism.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Azole antifungals

Schedule

Schedule H

[Internet]. 2017 [cited 23 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/10059

DailyMed - Voriconazole tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 23 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=16a80777-f1f3-45bb-a312-998b07767fe3

Voritek Tablets/Injection [Internet]. CiplaMed. 2020 [cited 22 January 2020]. Available from:

https://www.ciplamed.com/content/voritek-tabletsinjection

Voriconazole - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB00582

[Internet]. Accessdata.fda.gov. 2020 [cited 22 January 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021266s032lbl.pdf
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Information on this page was last updated on 28 Jan 2020

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