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Vokanamet 50/500 Tablet
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Vokanamet 50/500 Tablet

Manufactured byJOHNSON &JOHNSON
ContainsCanagliflozin (50 mg) + Metformin (500 mg)
Description
Vokanamet 50/500 Tablet is a combination of Canagliflozin and Metformin. It is used alone or in a combination with other medicines to treat type 2 diabetes (high blood sugar levels when your body cannot make, or use the insulin it makes, effectively to move sugar from the blood into the cells) in adults. This medicine works by lowering the blood sugar level in your body. Vokanamet 50/500 Tablet has some side effects like increased thirst, constipation, dry mouth, etc. These side effects may subside by themselves. Consult your doctor if it bothers you for a longer time or worsens. Vokanamet 50/500 Tablet is usually taken once a day before the first meal of your day. Avoid taking more than the recommended dose as it may increase the risk of undesired effects. Your doctor will suggest the dose and duration of treatment depending on the severity of your condition. Take it every day at the same time for the ease of remembering. Avoid discontinuing this medicine without consulting your doctor, as it can lead to an increased risk of high blood sugar levels and related complications. Vokanamet 50/500 Tablet is not recommended for use if you are allergic to it. Inform your doctor if you have liver or kidney problems or other health conditions. Also, inform your doctor about all your ongoing medications to avoid undesired effects. Vokanamet 50/500 Tablet is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established. Consult your doctor if you are pregnant or are breastfeeding before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Vokanamet 50/500 Tablet

  • Increased thirst
  • Dry mouth
  • Constipation
  • Indigestion
  • Headache
  • Diarrhoea
  • Chest pain
  • Skin rash

Uses of Vokanamet 50/500 Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The onset of action of Vokanamet 50/500 Tablet is not clinically established.
  • How long do the effects of this medicine last?
    The effect of Vokanamet 50/500 Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consuming alcohol during treatment with Vokanamet 50/500 Tablet as it may alter the blood sugar levels.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Vokanamet 50/500 Tablet.
  • Can this medicine be taken during pregnancy?
    Vokanamet 50/500 Tablet is not recommended for use in pregnancy as it may harm your developing foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Vokanamet 50/500 Tablet is not recommended for use while breastfeeding unless necessary. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Vokanamet 50/500 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Vokanamet 50/500 Tablet is not recommended for use in pregnancy as it may harm your developing foetus. Consult your doctor if you are pregnant.

Breast-feeding

Vokanamet 50/500 Tablet is not recommended for use while breastfeeding unless necessary. Hence, consult your doctor if you are breastfeeding.
General warnings

Lactic acidosis

Use of Vokanamet 50/500 Tablet may cause lactic acidosis. It is a condition of acid built up in your body characterized by low oxygen level, muscle cramps, abdominal pain, etc. If you experience these symptoms consult your doctor on priority.

Kidney function

The efficacy of Vokanamet 50/500 Tablet is dependent on the healthy functioning of your kidney. The effectiveness of this medicine may be reduced if you have a moderate kidney problem or if you are an elderly person with reduced kidney activity.

Amputaion

Vokanamet 50/500 Tablet should be used with caution as it may increase the risk of lower leg amputation (removal of a part, or multiple parts, of the leg or feet). The risk is higher if you have a history of leg amputation, foot ulcer, nerve damage, circulatory (blood flow), and heart problem.

Use in children

Vokanamet 50/500 Tablet is not recommended for use in children less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving and operating machines

Very low or high blood pressure may cause dizziness. Avoid driving or operating machines if you experience dizziness while you are on treatmentent with Vokanamet 50/500 Tablet.

Missed Dose

The missed dose of Vokanamet 50/500 Tablet is be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Never take more than the recommended dose. Seek emergency medical treatment in case of an overdose with Vokanamet 50/500 Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consuming alcohol during treatment with Vokanamet 50/500 Tablet as it may alter the blood sugar levels.
Interaction with Medicine

Furosemide

Digoxin

Carbamazepine

Gatifloxacin

Ciprofloxacin

Amlodipine

Acetazolamide

Disease interactions

Kidney dysfunction

Use Vokanamet 50/500 Tablet with caution if you have a kidney problem due to the increased risk of severe side effects. Your doctor may suggest close monitoring of kidney function if necessary while receiving this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Vokanamet 50/500 Tablet exactly as prescribed by your doctor. Your dose is likely to change over time based on your therapeutic response and clinical condition. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. Do not change the dose or duration of use without consulting your doctor. If you experience very low blood sugar levels and feel hungry, anxious, or dizzy, it is recommended to take sugar-containing fruits or drinks in order to balance it.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Vokanamet 50/500 Tablet is a combination of Canagliflozin and Metformin. Canagliflozin reduces sugar reabsorption from the kidneys and lowers blood glucose levels. Metformin decreases glucose production in your liver and decreases glucose absorption from the intestine making it more sensitive to insulin.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

SGLT-2 inhibitors, Non-sulfonylureas, Oral Biguanides, Antidiabetic combinations

Schedule

Schedule H

Drugs, H., 2021. Canagliflozin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 18 October 2021].

https://medlineplus.gov/druginfo/meds/a613033.html#precautions

Pubchem.ncbi.nlm.nih.gov. 2021. Canagliflozin. [online] Available at: [Accessed 18 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Canagliflozin

Medicines.org.uk. 2021. Invokana 100 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 18 October 2021].

https://www.medicines.org.uk/emc/product/8855/smpc

U.S. Food and Drug Administration. 2021. FDA confirms risk of leg and foot amputations with the diabetes. [online] Available at: [Accessed 18 October 2021].

https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-confirms-increased-risk-leg-and-foot-amputations-diabetes-medicine

Pubchem.ncbi.nlm.nih.gov. 2021. Metformin. [online] Available at: [Accessed 21 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/4091#section=Biological-Half-Life

Medicines.org.uk. 2021. Vokanamet 50 mg/1000 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 21 October 2021].

https://www.medicines.org.uk/emc/product/8261/smpc#POSOLOGY
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Information on this page was last updated on 6 Feb 2023

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.