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Vingraf 1 MG Capsule

Manufactured by: Emcure Pharmaceuticals Ltd.
Composition: Tacrolimus
Prescription Required: Yes
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Description

Vingraf 1 MG Capsule is an immuno-suppressant which is used in kidney, liver, and heart transplant patients. It should be used under the supervision of a qualified physician. Close monitoring of blood pressure is necessary while receiving this medicine.

Side effects

Major & minor side effects for Vingraf 1 MG Capsule

  • Abdominal painsevere
  • Diarrheasevere
  • Dizzinesssevere
  • Headachesevere
  • Swelling of feet or lower legssevere
  • Blurred visionsevere
  • Sweatingsevere
  • Weight losssevererare
  • Acid or sour stomach
  • Loss of strength
  • Body pain
  • Scaly skin
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Vingraf 1 MG Capsule

Onset of action

The effect of this medication can be observed in 0.5 to 6 hours.

Duration of effect

The effect of this medicine lasts for an average duration of 2 to 4 days for an immediate release tablet and 3 to 5 days for an extended release tablet.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for pregnant women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?

This medicine is known to excreted in breast milk. It is not recommended in breastfeeding women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

Substitutes

List of substitutes for Vingraf 1 MG Capsule

Below is the list of medicines, which have the same composition, strength and form as Vingraf 1 MG Capsule, and hence can be used as its substitute.
Crolim 1 MG Capsule
Ranbaxy Laboratories Ltd.
Rengraf 1 MG Capsule
Abbott Healthcare Pvt. Ltd.
Taclicept 1 MG Capsule
Lupin Ltd.
Tacromus 1 MG Capsule
Zydus Cadila
Tacsant 1 MG Capsule
Novartis India Ltd.

What is it prescribed for?

Uses of Vingraf 1 MG Capsule

  • Organ Transplant - Rejection Prophylaxis

    Vingraf 1 MG Capsule is used to reduce the immune response of the body in organ transplant patients.

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When not to use?

Contraindications of Vingraf 1 MG Capsule

  • Allergy

    Not recommended in patients with known allergy to Vingraf 1 MG Capsule.

Dosage

  • Missed Dose

    If you miss a dose of Vingraf 1 MG Capsule, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Diabetes Mellitus

    severe
    This medicine may cause a condition called post-transplant insulin-dependent diabetes mellitus. Insulin should be administered in these patients. Close monitoring of glucose levels is necessary.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Vingraf 1 MG Capsule under the supervision of a qualified healthcare professional. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for pregnant women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    - This medicine is known to excreted in breast milk. It is not recommended in breastfeeding women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

General warnings

  • Malignancy

    - This medicine may increase the risk of lymphoma and other malignancies. Doctors should inform patients about these risks and advise the patient to [revent exposure of the sunlight by wearing protective clothes.

  • Serious infections

    - The chances of occurring infections are more in the patients receiving this medicine. Hold the treatment and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

  • Liver impairment

    - This medicine is not recommended in the patients with a history of liver impairment. The concentration of this medicine may increase in these patients. The baseline of the liver function tests should be obtained before starting the treatment.

  • Kidney impairment

    - This medicine is not recommended in the patients with a history kidney impairment. Close monitoring of kidney function is necessary. The dose should be adjusted based on the creatine clearance (CrCl).

  • Hypertension

    - Use with caution in hypertensive patients. Appropriate antihypertensives should be administered to control the blood pressure. Do not use medicine that may increase the potassium levels.

  • Hyperkalemia

    - This medicine may increase the levels of potassium in the body and may increase the risk of arrhythmia. Close monitoring of potassium levels is necessary. Medicines that can increase the potassium levels like ACE inhibitors and potassium-sparing diuretics should be avoided.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

It works by decreasing the body's immune system activity and helps in preventing body's rejection action of transplanted organs.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Calcineurin inhibitors
Schedule
Schedule H

References

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.