Velpatasvir

Description

Velpatasvir is an antiviral medicine used in combination with other medicines for the treatment of chronic hepatitis C infection. This medicine should be used with extreme caution in patients with a known history of hepatitis B infection due to the increased risk of serious adverse reactions.

Side effects

Major & minor side effects for Velpatasvir

  • Fatigue
  • Difficulty in breathing
  • Cough
  • Itching
  • Headache
  • Nausea
  • Diarrhea

Uses of Velpatasvir

What is it prescribed for?

  • Chronic Hepatitis C
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to velpatasvir or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Use in pediatrics

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Hepatitis B

This medicine should be used with extreme caution in patients with a known history of hepatitis B due to the increased risk of reactivation of hepatitis B infection. This may cause serious liver problems including liver failure and death. Screening for hepatitis B prior to beginning treatment, close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antacids

Efavirenz

Phenytoin

Carbamazepine

Rifampicin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by stopping the hepatitis C virus from multiplying in the body. This helps in stopping the spread of the infection.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Miscellaneous antivirals

Schedule

Schedule H

Velpatasvir - DrugBank [Internet]. Drugbank.ca. 2018 [cited 9 April 2018]. Available from:

https://www.drugbank.ca/drugs/DB11613

Velpatasvir [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 9 April 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Velpatasvir#

[Internet]. 2018 [cited 9 April 2018]. Available from:

https://www2.medicines.org.uk/emc/medicine/32177

[Internet]. Accessdata.fda.gov. 2018 [cited 9 April 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208341s000lbl.pdf

[Internet]. Gilead.com. 2018 [cited 9 April 2018]. Available from:

https://www.gilead.com/~/media/files/pdfs/medicines/liver-disease/epclusa/epclusa_pi.pdf

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Information on this page was last updated on 10 Apr 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.