Vasopressin

Description

Vasopressin is a man-made form of an anti-diuretic hormone that is secreted by the pituitary gland. It is used in the treatment of diabetes insipidus (a condition characterized by intense thirst and heavy urination). It is also used to raise the blood pressure levels in patients with shock (a condition that results from lack of blood flow). This medicine helps to treat or prevent certain conditions of the stomach after surgery (postoperative abdominal distension) and during abdominal x-rays.

Side effects

Major & minor side effects for Vasopressin

  • Chest pain
  • Dizziness
  • Skin Rash
  • Sweating
  • Vomiting
  • Nausea
  • Headache
  • Injection site pain
  • Pale skin

Uses of Vasopressin

What is it prescribed for?

  • Diabetes insipidus
  • Hypotension due to shock
  • Abdominal Radiological Procedure
  • Abdominal Distension
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 2-8 hours on an intramuscular or subcutaneous administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to vasopressin or any other inactive ingredients present along with it.

Chronic nephritis

This medicine is not recommended for use in patients with chronic nephritis (inflammation of kidneys) with nitrogen retention due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Heart diseases

This medicine should be used with caution in patients with heart diseases due to the increased risk of worsening of the patient's condition. Close monitoring of cardiac function is necessary while receiving this medicine together. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Renal diseases

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function tests is necessary while receiving this medicine together. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Seizures

This medicine should be used with caution in patients with seizures due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Asthma

This medicine should be used with caution in patients with asthma due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Fluid restriction

This medicine may lead to water intoxication and/or very low blood sodium levels which may be fatal in some patients. Hence, fluid restriction is recommended during treatment with this medicine, especially when the medicine is not used to control increased urination. Report any symptoms such as a headache, nausea, vomiting, weight gain, restlessness, fatigue, lethargy, disorientation, depressed reflexes, loss of appetite, irritability, muscle weakness, muscle spasms or cramps, hallucinations, decreased levels of consciousness, confusion, etc. to the doctor immediately. Close monitoring of blood sodium levels, appropriate patient/caregiver counseling, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Ziprasidone

Amiodarone

Cisapride

Bedaquiline

Iloperidone

Disease interactions

Vascular Diseases

This medicine should be used with extreme caution in patients with vascular diseases due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts on the kidneys and reduces urine production. It helps to raise the blood pressure by narrowing the blood vessels.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antidiuretic hormones

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 6 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/204485Orig1s000lbl.pdf

Vasopressin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 6 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00067

Vasopressin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 6 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/644077

Argipressin 20 IU/ml Solution for Injection - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 28 January 2019]. Available from:

https://www.medicines.org.uk/emc/product/4117

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Information on this page was last updated on 28 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.