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Vasograin Tablet
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Vasograin Tablet

Manufactured byCADILA PHARMACEUTICALS LTD
ContainsErgotamine (1 mg) + Caffeine (100 mg) + Paracetamol (250 mg) + Prochlorperazine (2.5 mg)
Description
Vasograin Tablet is a medicine that consists of Ergotamine, Caffeine, Paracetamol and Prochlorperazine. It is used for the treatment of migraine headaches (a throbbing pain mostly on one side of the head). This medicine also helps to relieve the symptoms such as nausea and vomiting of migraine headaches. Vasograin Tablet works by blocking the release of certain chemicals that cause pain and swelling. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches. Vasograin Tablet may cause side effects like dryness of mouth, constipation, difficulty while urinating, sudden decrease in blood pressure, etc. Consult your doctor if any of these side effects persist for a long time. Vasograin Tablet may cause drowsiness. Hence, avoid driving vehicles or operating machines after taking the medicine. Avoid using this medicine if you are allergic to it. Vasograin Tablet should be taken only if it is prescribed by your doctor. This medicine should be taken with food to avoid gastric irritation. The dosage and duration of the treatment will be decided by your doctor based on the severity of your condition and other underlying problems. Do not stop taking this medicine without consulting your doctor. Vasograin Tablet is not recommended for use in children below 16 years of age. Inform your doctor if you have liver or kidney problems before taking this medicine. Vasograin Tablet is known to shown serious side effects to the developing foetus. Hence, inform your doctor if you are pregnant or planning a pregnancy, before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Vasograin Tablet

  • Gastric / mouth ulcer
  • Bloody and cloudy urine
  • Unsual tiredness or weakness
  • Constipation
  • Dry mouth
  • Irregular heartbeat
  • Drowsiness
  • Skin rash
  • Chest pain
  • Pain or swelling in the legs
  • Muscle cramps
  • Itching
  • Burning or tingling sensation

Uses of Vasograin Tablet

What is it prescribed for?

  • Migraine headache
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for Vasograin Tablet to show its action is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Vasograin Tablet remains effective in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Vasograin Tablet due to the increased risk of serious side effects such as dizziness, fatigue, weakness, nausea, etc.
  • Is this a habit forming medicine?
    Vasograin Tablet may become habit-forming with prolonged use and if recommended doses are exceeded.
  • Can this medicine be taken during pregnancy?
    Vasograin Tablet is not recommended for use in pregnancy as it may harm your foetus. Hence, consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Vasograin Tablet is not recommended if you are breastfeeding as this medicine is passed into the breast milk. It may harm your infant. Hence, consult your doctor before using this medicine.

Allergy

Avoid taking Vasograin Tablet if you are allergic to it. Seek medical attention immediately if you notice any symptoms such as skin rash, itching/swelling anywhere in the body, dizziness, breathing difficulty, etc.

Severe liver disease

Vasograin Tablet is broken down and absorbed in the liver. A damaged liver cannot absorb this medicine effectively, leading to its accumulation. This may damage your liver and worsen your condition. Avoid taking Vasograin Tablet if you have pre-existing liver problems.

Depression

Vasograin Tablet is not recommended for use if you have symptoms of depression as it may cause serious side effects.

CYP3A4 inhibitors

Vasograin Tablet is not recommended for use if you are taking taking CYP3A4 inhibitors (medicines used to treat fungal infections) due to the increased risk of serious side effects.
Warnings for special population

Pregnancy

Vasograin Tablet is not recommended for use in pregnancy as it may harm your foetus. Hence, consult your doctor before using this medicine.

Breast-feeding

Vasograin Tablet is not recommended if you are breastfeeding as this medicine is passed into the breast milk. It may harm your infant. Hence, consult your doctor before using this medicine.
General warnings

Neuroleptic malignant syndrome

Vasograin Tablet should be discontinued immediately if you develop Neuroleptic malignant syndrome (a serious neurologic emergency condition caused by the use of antipsychotic (neuroleptic) agents) characterized by an increase in body temperature, muscle rigidity, altered consciousness.

Heart diseases

Vasograin Tablet should be used with caution if you have heart or heart valve problems as it may increase your blood pressure and affect other functions of your heart. Your doctor may suggest tests for monitoring your heart function while on treatment with this medicine. Also, he may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

Driving or operating machines

Vasograin Tablet may cause sleepiness or dizziness. Hence, avoid driving vehicles and operating heavy machines after taking this medicine.

Use in children

Vasograin Tablet is not recommended for use in children under the age of 18 years as the safety and efficacy data is not available.

Missed Dose

If you forget to take a dose of Vasograin Tablet, take it as soon as you remember. If it is time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose of Vasograin Tablet. If you suspect that you might have taken an overdose of this medicine, seek immediate medical attention.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Vasograin Tablet due to the increased risk of serious side effects such as dizziness, fatigue, weakness, nausea, etc.
Interaction with Medicine

Carbamazepine

Phenytoin

Sodium Nitrite

Leflunomide

Antidiabetic medicines

Antihypertensives

Disease interactions

Liver disease

Vasograin Tablet may increase liver enzyme levels. Hence, it should be used with caution if you have liver problems as it can increase the risk of liver damage.

Kidney diseases

Vasograin Tablet is filtered by the kidney and excreted through urine. Hence, it should be used with caution if you have kidney problems as it can increase the risk of serious side effects.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

5-HIAA urine test measures the amount of serotonin (a key hormone that stabilizes our mood, feelings of well-being, and happiness) in your body. Vasograin Tablet can interfere with urine tests and may give a false-positive result. Inform your doctor and lab technician about all your current medicines before undergoing any lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Vasograin Tablet is used in treating migraine headache. Take this medicine with food or as prescribed by your doctor. Avoid taking more doses of Vasograin Tablet than prescribed. Consult your doctor if you experience any undesirable effects. Take Vasograin Tablet at around the same time daily. Do not stop taking this medicine without consulting your doctor. Vasograin Tablet may cause dizziness. Hence, driving vehicles after taking the medicine. Consumption of alcohol is not recommended during treatment with Vasograin Tablet due to the increased risk of serious side effects such as dizziness, fatigue, weakness, nausea, etc. Keep the medicine away from the reach of children and pets. Ensure that unused medicine is disposed of properly.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
Ergotamine works by preventing blood vessels in the head from expanding and causing headaches. Caffeine increases the absorption of ergotamine and paracetamol and further narrows the widened blood vessels and reduces the pain. Paracetamol works by blocking the release of certain chemicals that are responsible for causing pain, swelling and fever. Prochlorperazine works by binding to certain receptors and blocks the release of chemical substances that cause nausea and vomiting.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antimigraine combinations

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Ergotamine. [online] Available at: < [Accessed 5 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/ergotamine>

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Drugs, H., 2021. Prochlorperazine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 5 October 2021].

https://medlineplus.gov/druginfo/meds/a682116.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Caffeine. [online] Available at: < [Accessed 5 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Caffeine>
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Information on this page was last updated on 8 Oct 2021

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