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VALZAAR SM CAPSULE

Manufactured byTorrent Pharmaceuticals Ltd.
ContainsS-Amlodipine (2.5 mg) + Valsartan (80 mg)
Description

VALZAAR SM CAPSULE is a combination medicine used for the treatment of high blood pressure. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.

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Side effects

Major & minor side effects for VALZAAR SM CAPSULE

  • Weakness in arms, hands, legs or feet
  • Dizziness
  • Abdominal pain
  • Difficult or painful urination
  • Back pain
  • Chest tightness
  • Nasal congestion
  • Sore throat
  • Irregular heartbeat
  • Black or tarry stools
  • Blurred vision
  • Diarrhea
  • Flushing
  • Pruritus
  • Rash
  • Nausea and Vomiting
  • Headache

Uses of VALZAAR SM CAPSULE

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is about 2 hours.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to S-amlodipine, other calcium-channel blockers, valsartan, or any other angiotensin receptor blockers.

Aliskiren

Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypotension

Symptomatic hypotension may occur in patients with volume depletion or patients who are treated with high doses of diuretics. It is advised to correct the condition before beginning treatment with this medicine.

Hyperkalemia

This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine.

Impaired liver function

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Pediatric population

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Primary hyperaldosteronism

This medicine is not recommended for use in patients with primary hyperaldosteronism since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Renal artery stenosis

This medicine should be used with caution in patients with renal artery stenosis due to the increased risk of severe adverse effects. Close monitoring of blood urea and serum creatinine levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving and operating machines

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Aortic stenosis

This medicine should be used with extreme caution in patients suffering from aortic stenosis due to the increased risk of a very low blood pressure. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired renal function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function and electrolytes levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Itraconazole

Corticosteroids

Rifampicin

Aliskiren

Captopril

Insulin

Nonsteroidal anti-inflammatory medicines

Disease interactions

Angioedema

This medicine is not recommended for use in patients with a known history of angioedema due to the increased risk of worsening of the patient's condition. Report any symptoms such as swelling of the face or lips, difficulty swallowing, or difficulty breathing to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Renal impairment

This medicine should be used with caution in patients with a known history of renal impairment since it may worsen the patient's condition. Close monitoring of kidney function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.

Coronary Artery Disease

This medicine should be used with extreme caution in patients with coronary artery diseases due to the increased risk of worsening of the patient's condition. Close monitoring of vital signs and heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Congestive heart failure

This medicine should be used with caution in patients with congestive heart failure since it may worsen the patient's condition. Close monitoring of blood pressure, electrolytes level, and heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Coadministration of multivitamin with minerals and this combination medicine may decrease the effects of this medicine. Close monitoring of blood pressure and appropriate dose adjustments may be necessary in some cases based on the clinical condition.
It is recommended to avoid a high potassium diet during treatment with this medicine due to the increased risk of serious adverse effects. Your doctor/dietitian will suggest an appropriate diet for you to avoid high intake of potassium.
Lab interactions
Information not available.
Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
S-Amlodipine relaxes the heart muscles and the blood vessels. Valsartan relaxes the blood vessels and promotes the smooth flow of blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Angiotensin receptor blockers, Antihypertensive combinations, Angiotensin II inhibitors with calcium channel blockers

Schedule

Schedule H

[Internet]. 2017 [cited 25 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/30901

DailyMed - Valsartan tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 25 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9402b022-5809-4251-dfef-54f6ef5723fe

Valsartan: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 25 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a697015.html

DailyMed - Amlodipine besylate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 3 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b
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Information on this page was last updated on 13 Nov 2017

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