Warnings for special population
This medicine is recommended for use in pregnant women only when absolutely necessary and the potential benefits outweigh the risks involved. Preservative free forms are recommended for administration.
This medicine is recommended for use in breastfeeding women only when absolutely necessary and the potential benefits outweigh the risks involved. Preservative free forms are recommended for administration.
Hemorrhage and risk factors
Use of this medicine should be initiated only after internal bleeding or hemorrhage and associated risk factors are ruled out. All the underlying causes of bleeding such as peptic ulcer disease, hemophilia, impaired hemostasis, etc. should also be ruled out before the administration of this medicine.
Use of this medicine may cause low levels of platelets (thrombocytopenia). It is advised to monitor the blood platelet levels at regular intervals while this medicine is administered. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Use in elderly
This medicine should be used with extreme caution in the elderly population since the risk of adverse effects is significantly high. Appropriate dose adjustments and frequent clinical monitoring are advised for such patients to safely use this medicine.
Benzyl alcohol as preservative
Dosage forms containing benzyl alcohol as a preservative should not be administered to neonates, infants, and pregnant or breastfeeding women. Benzyl alcohol may cause a fatal adverse event known as Gasping syndrome in neonates and infants.
This medicine should be used with caution in patients having an impairment of normal liver/kidney function. Appropriate dose adjustments and frequent clinical monitoring are recommended for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition.
Use of this medicine may cause an increase in blood potassium levels (hyperkalemia) and associated complications. Close monitoring of potassium levels may be necessary based on the clinical condition.
Use of this medicine in high doses for a prolonged duration may cause osteoporosis and associated complications.
This medicine may interact with many other medicines and may cause severe side effects. Hence, you are advised to report the use of all medicines including herbs and supplements to the doctor before beginning treatment with this medicine.
Occurrence of side effects
It is possible that you may experience certain side effects after the use of this medicine has been stopped. Report any instances of unusual symptoms to the doctor immediately.
Smoking and use of tobacco products
Inform the doctor about your smoking habits or use of tobacco in any form before treatment with this medicine is initiated. Use of tobacco products may decrease the effectiveness of this medicine.
The intravenous form of this medicine should not be mixed with certain diluents and medicines due to incompatibility. Caution should be exercised while picking the diluent and other medicines at the time of administration.