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Ursodox 250 MG Syrup
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Ursodox 250 MG Syrup

Manufactured bySignova Pharma Pvt. Ltd.
ContainsUrsodeoxycholic Acid
Description
Ursodox 250 MG Syrup is a medicine used to dissolve gallstones that are composed mainly of undissolved cholesterol. It is also used to improve the flow of bile in Primary Biliary Cirrhosis (a chronic condition in which the bile ducts in your liver are slowly damaged and destroyed). It works by breaking down the cholesterol in gallstones which helps in dissolving the stones. It improves the functioning of liver enzymes and protects liver cells. Ursodox 250 MG Syrup may cause side effects like stomach ache, itching, nausea, vomiting, pain during passing urine, cough, etc. These side effects usually subside with time. However, consult your doctor for further assistance if they persist or worsen. Ursodox 250 MG Syrup should be taken after a meal with a glass of milk or water. Your doctor will recommend the appropriate dose and duration of treatment based on your clinical condition and therapeutic response. Do not stop taking this medicine without consulting your doctor. Ursodox 250 MG Syrup is not recommended if you are allergic to it. It should be avoided if you have any obstruction in your liver or gallbladder. Inform your doctor about all your clinical conditions and ongoing medications you are taking to avoid any interaction. It should be taken during pregnancy or breastfeeding only after consulting your doctor. It is not recommended for children below 18 years of age.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Ursodox 250 MG Syrup

  • Diarrhoea
  • Indigestion
  • Bladder pain
  • Nausea or Vomiting
  • Unusual bleeding
  • Weakness

Uses of Ursodox 250 MG Syrup

What is it prescribed for?

  • Dissolution of cholesterol rich gallstones
  • Primary biliary cirrhosis (bile acid associated liver damage)
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for Ursodox 250 MG Syrup to show its effect is variable and depends on stone size and composition. It may start showing its effect after six to 24 months after the administration.
  • How long do the effects of this medicine last?
    The time for which Ursodox 250 MG Syrup remains effective in the body is subject to vary depending on the use.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Ursodox 250 MG Syrup.
  • Can this medicine be taken during pregnancy?
    Ursodox 250 MG Syrup should be used by pregnant women only when clearly needed. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is unknown if the medicine passes into the breast milk or not. Ursodox 250 MG Syrup should be used with caution if you are breastfeeding. Consult your doctor before taking this medicine.

Allergic reaction

Avoid taking Ursodox 250 MG Syrup if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Biliary tract disorder

Ursodox 250 MG Syrup is not recommended for use if you have a biliary tract disorder such as swelling, obstruction, deformation, or fistula of the bile tract.

Gallbladder disorder

Ursodox 250 MG Syrup is not recommended for use if you have a non-functional gall bladder or conditions like swelling or impaired contractility of the gall bladder.

Presence of calcified gallstone

Ursodox 250 MG Syrup is not recommended for use if you have gallstones that have formed due to a deposit of calcium. These stones are detectable through X-ray.

Chronic liver disease

Ursodox 250 MG Syrup is not recommended for use if you have impaired liver function as it may worsen your condition.

Inflammatory bowel disease

Inflammatory bowel disease is a condition that causes chronic swelling, irritation, and pain of the intestine that may lead to bleeding. Ursodox 250 MG Syrup is not recommended for use in people with an ongoing inflammatory disease of the bowel.

Patients requiring cholecystectomy

Ursodox 250 MG Syrup is not recommended for use in people who require surgery to remove the gall bladder or need surgery to remove the stones.
Warnings for special population

Pregnancy

Ursodox 250 MG Syrup should be used by pregnant women only when clearly needed. Consult your doctor before taking this medicine.

Breast-feeding

It is unknown if the medicine passes into the breast milk or not. Ursodox 250 MG Syrup should be used with caution if you are breastfeeding. Consult your doctor before taking this medicine.
General warnings

Type of gallstones

Ursodox 250 MG Syrup should be used only if the stone has high cholesterol content. Other stones formed due to calcium deposits or ones that are detectable in X-ray should not be treated with this medicine.

Liver disease

Ursodox 250 MG Syrup should be used with caution in people with liver impairment. Your doctor may recommend close monitoring of your liver function and bilirubin levels before and during the course of treatment with this medicine.

Time taken for stone dissolution

Ursodox 250 MG Syrup may take several months to dissolve the gall stone. Report any side effects you experience during this period to your doctor immediately. Do not discontinue treatment before the course is complete as it may result in the recurrence of stone formation.

Diarrhoea

Report any incidence of diarrhoea while taking Ursodox 250 MG Syrup to your doctor immediately. Your doctor may recommend appropriate dose adjustments if this side effect is severe and persistent.

Initial worsening of symptoms

Use of Ursodox 250 MG Syrup for primary biliary cirrhosis may worsen the symptoms initially. Report any such instance to the doctor as a dose adjustment may be needed in such cases.

Use in children

Ursodox 250 MG Syrup is not recommended for use in children younger than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Do not miss the dose of Ursodox 250 MG Syrup. In case you miss a dose, take it as soon as you remember. However, if it is time for the next dose, then skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose of Ursodox 250 MG Syrup. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Ursodox 250 MG Syrup as instructed by your doctor. For tablet/capsule form: Do not break, chew, or crush the medicine in your mouth. Swallow as a whole with plenty of water. Follow all the instructions given on the prescription label or packing insert. For suspension/syrup: Shake the bottle well before use. Do not take it in larger or smaller quantities than recommended. Take the medicine for the recommended duration. Do not discontinue this medication abruptly without consulting your doctor as it may cause a recurrence of gallstones. Eat a healthy diet, exercise regularly, and avoid alcohol intake while undergoing treatment with Ursodox 250 MG Syrup. Diarrhoea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhoea persists or if you find blood in your stools. Your doctor may monitor your liver function and bilirubin levels every month for the next three months after the start of treatment, and every six months thereafter.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Ursodox 250 MG Syrup works by inhibiting the production of cholesterol from the liver and also reducing the absorption of cholesterol from the intestine. It improves the functioning of liver enzymes and protects liver cells.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Gallstone solubilizing agents

Schedule

Schedule H

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https://www.medicines.org.uk/emc/product/7253/smpc#gref

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https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020675s017lbl.pdf

Mayoclinic.org. 2021. Ursodiol (Oral Route) Description and Brand Names - Mayo Clinic. [online] Available at: [Accessed 13 January 2022].

https://www.mayoclinic.org/drugs-supplements/ursodiol-oral-route/description/drg-20066618

Cleveland Clinic. 2022. Ursodeoxycholic Acid, Ursodiol capsules or tablets. [online] Available at: [Accessed 13 January 2022].

https://my.clevelandclinic.org/health/drugs/20178-ursodeoxycholic-acid-ursodiol-capsules-or-tablets

(no date) Ursodeoxycholic acid 250 mg capsules - summary of product characteristics (SmPC) - (EMC). Available at: (Accessed: April 17, 2023).

https://www.medicines.org.uk/emc/product/7253/smpc#:~:text=Adults%3A%20The%20usual%20dose%20is,on%20stone%20size%20and%20composition.
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Information on this page was last updated on 18 Apr 2023

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