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Unifen MR Tablet

Manufactured byUNIMARK HEALTHCARE LTD
ContainsDiclofenac (50 mg) + Paracetamol (325 mg) + Methocarbamol (500 mg)
Description

Unifen MR Tablet is a combination medicine that may be used for the treatment of mild to moderate pain associated with muscle spasm such as low back pain, neck pain, sprains/strains, etc. Patients are advised to undergo appropriate physical therapy and rest along with this medicine to obtain the best possible effect.

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Side effects

Major & minor side effects for Unifen MR Tablet

  • Nausea or Vomiting
  • Gastric / Mouth Ulcer
  • Bloody and cloudy urine
  • Anemia
  • Fatigue
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Skin rash
  • Ringing in ears
  • Dizziness when getting up suddenly from a sitting position
  • Lightheadedness
  • Blurred vision
  • Stomach upset
  • Drowsiness

Uses of Unifen MR Tablet

What is it prescribed for?

  • Mild to Moderate Pain associated with Muscle Spasm
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to diclofenac, paracetamol, methocarbamol, or any other inactive ingredients present in the formulation.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening the patient's condition.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe adverse reactions.

Gastro-intestinal bleeding

This medicine is not recommended for use in patients with a known history of gastrointestinal bleeding due to the increased risk of worsening of the patient's condition.

Cardiovascular Disease

This medicine is not recommended for use in patients with a known history of cardiovascular diseases due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Effect on heart

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Coronary Artery Bypass Surgery

This medicine should not be taken to relieve pain before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe adverse reactions.

Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Skin allergies

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Driving or operating machinery

This medicine may cause dizziness, blurred vision, drowsiness, etc in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amitriptyline

Carbamazepine

Fluvoxamine

Methotrexate

Phenytoin

Ramipril

Tramadol

Sodium Nitrite

Leflunomide

Prilocaine

Adefovir

Apixaban

Ketorolac

Sodium oxybate

Meprobamate

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Heart attack and Stroke

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine exactly as prescribed by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Diclofenac and Paracetamol inhibit the formation of certain natural substances that are responsible for causing pain and inflammation. Methocarbamol blocks the pain signals from reaching the brain. Thus, this combination is better effective in relieving pain, swelling, and inflammation associated with muscle spasms.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Miscellaneous analgesics, Muscle relaxants

Schedule

Schedule H

Methocarbamol - DrugBank [Internet]. Drugbank.ca. 2017 [cited 30 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00423

Methocarbamol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682579.html

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

Acetaminophen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681004.html

Diclofenac | C14H11Cl2NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 23 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3033

Diclofenac: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 6 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a689002.html
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Information on this page was last updated on 9 Jan 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.