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Unicarbazan Forte Tablet
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Unicarbazan Forte Tablet

Manufactured byTORRENT PHARMACEUTICALS LTD
ContainsDiethylcarbamazine (250 mg) + Chlorpheniramine (5 mg)
Description
Unicarbazan Forte Tablet is a combination medicine which may be used for prevention and treatment of worm infections such as tropical pulmonary eosinophilia, filariasis, loiasis, etc. It is not recommended to prevent or treat the infections caused by pinworms and tapeworms.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Unicarbazan Forte Tablet

  • Fever
  • Tender, swollen glands in the neck
  • Skin rash
  • Visual disturbances
  • Nausea
  • Dizziness
  • Sleepiness or unusual drowsiness
  • Dry mouth

Uses of Unicarbazan Forte Tablet

What is it prescribed for?

  • Lymphatic Filariasis (Elephantiasis)
  • Loiasis (African eye worm)
  • Toxocariasis
  • Tropical pulmonary eosinophilia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving this medicine due to the increased risk of drowsiness, dizziness, and difficulty in concentrating. It is advised that you do not consume alcohol or limit its use when being treated. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Diethylcarbamazine, Chlorpheniramine or any other inactive ingredients present in the formulation.

Onchocerciasis (River blindness)

Patients being treated with this medicine for onchocerciasis may experience Mazzotti reaction which may be characterized by fever, headache, dizziness, vomiting, lymphangitis, or asthmatic attacks. These patients should be monitored closely and supportive care should be initiated based on the severity of the reaction.

Benign prostatic hyperplasia

This medicine is not recommended for use in patients with benign prostatic hyperplasia (enlarged prostate) since it may cause increased difficulty in passing urine.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Prolonged use

Prolonged use of this combination medicine may cause tunnel vision, night blindness, or loss of vision.

Use in severely ill patients

Do not use this medicine in severely ill patients with other acute diseases until their recovery.

Epilepsy

This medicine should be used with caution in patients with epilepsy since it increases the risk of seizures. An alternative treatment option may be necessary in some cases based on the clinical condition.

Heart Diseases

Use of this medicine is not recommended in patients with cardiac diseases due to the increased risk of severe side effects like tachycardia. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other medicines

This combination medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Liver/Kidney Disease

This medicine should be used with caution in patients with liver/kidney diseases due to the increased risk of adverse effects. Regular monitoring of liver/kidney function is necessary for such patients while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating heavy machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine due to the increased risk of drowsiness, dizziness, and difficulty in concentrating. It is advised that you do not consume alcohol or limit its use when being treated. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Anxiolytics

Antimalarial drugs

Disease interactions

Gastrointestinal blockage

This medicine is not recommended for use in patients with a gastrointestinal obstruction due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Glaucoma

This medicine is not recommended for use in patients with glaucoma due to the increased risk of a rise in intraocular pressure, leading to an increased risk of vision problems. This risk is especially higher in elderly patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with asthma/COPD since it may increase the risk of further lung problems like respiratory tract blockage. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken immediately after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Diethylcarbamazine acts on both the movement of the worms and the surface layer of the worms, making them easier to kill. The worms are then killed by the immune system of the body. Chlorpheniramine blocks the action of certain substances produced by the body which induces allergic reactions.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Anthelmintics, Antihistamines

Schedule

Schedule G

Diethylcarbamazine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB00711

WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition: Helminths: Lymphatic filariasis: Diethylcarbamazine [Internet]. Apps.who.int. 2017 [cited 19 July 2017]. Available from:

http://apps.who.int/medicinedocs/en/d/Jh2922e/3.5.1.html#Jh2922e.3.5.1

Chlorphenamine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01114

[Internet]. 2017 [cited 11 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/13691
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Information on this page was last updated on 7 Aug 2019

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