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Ultrazac (325/37.5 mg) Tablet

Manufactured byZydus Cadila
ContainsParacetamol (325 mg) + Tramadol (37.5 mg)
Description
Ultrazac (325/37.5 mg) Tablet is a combination of Paracetamol and Tramadol. This medicine is a painkiller that helps in relieving moderate to severe pain associated with muscle spasms or injury such as sprains/strains, injury due to accident, etc. Ultrazac (325/37.5 mg) Tablet works by blocking the formation of certain chemical substances responsible for pain and swelling. This medicine is most effective when taken along with proper rest and physical therapy. Ultrazac (325/37.5 mg) Tablet has some common side effects such as nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Seek a doctor's consultation if these side effects do not resolve with time or get worse. It is recommended not to use this medicine if you have been allergic to it. Ultrazac (325/37.5 mg) Tablet should be taken with food to avoid stomach irritation. Your doctor will advise you on the dose and duration of this medicine based on the severity of the pain. For the ease of remembering, take it at around the same time every day. This medicine should be used with extreme caution because it has a high potential for addiction and abuse even at recommended dosages, especially upon prolonged use. Ultrazac (325/37.5 mg) Tablet should be used with caution if you have liver and kidney disease. This medicine may increase the risk or worsen stomach ulcers and may cause bleeding therefore, use it with caution. To make sure Ultrazac (325/37.5 mg) Tablet is safe for you, share your entire medical and medication history with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.

Side effects

Major & minor side effects for Ultrazac (325/37.5 mg) Tablet

  • Nervousness
  • Dizziness
  • Headache
  • Blurred vision
  • Hot flushes
  • Shortness of breath
  • Nausea and Vomiting
  • Dry mouth
  • Abdominal pain
  • Indigestion
  • Rash
  • Chest pain
  • Constipation
  • Flatulence

Uses of Ultrazac (325/37.5 mg) Tablet

What is it prescribed for?

  • Moderate to severe pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Ultrazac (325/37.5 mg) Tablet can be observed within 1 hour of administration of the dose. However, you may start feeling well in few hours.
  • How long do the effects of this medicine last?
    The effect of Ultrazac (325/37.5 mg) Tablet lasts for an average duration of 9 hours. But you should take your next dose if needed.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while treatment with Ultrazac (325/37.5 mg) Tablet due to the risk of stomach bleeding, dizziness, fatigue, weakness.
  • Is this a habit forming medicine?
    Ultrazac (325/37.5 mg) Tablet may become habit-forming in some cases.
  • Can this medicine be taken during pregnancy?
    Ultrazac (325/37.5 mg) Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your foetus. But in some cases, your doctor may prescribe this medicine during the first 6 months of pregnancy if the benefits outweigh the risks. Discuss the benefits and risks with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Ultrazac (325/37.5 mg) Tablet is known to be excreted in breast milk. It should be avoided in breastfeeding mothers. However, if needed it should only be used upon your doctor's recommendation.

Allergy

Ultrazac (325/37.5 mg) Tablet can be avoided if you are allergic to it. Seek an immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Severe liver disease

Ultrazac (325/37.5 mg) Tablet is not recommended for use in case of severe liver disease due to the increased risk of worsening of the health condition.

Use in children

Ultrazac (325/37.5 mg) Tablet is not recommended for use in children less than 12 years of age as effective and safe use are not established.
Warnings for special population

Pregnancy

Ultrazac (325/37.5 mg) Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your foetus. But in some cases, your doctor may prescribe this medicine during the first 6 months of pregnancy if the benefits outweigh the risks. Discuss the benefits and risks with your doctor before taking this medicine.

Breast-feeding

Ultrazac (325/37.5 mg) Tablet is known to be excreted in breast milk. It should be avoided in breastfeeding mothers. However, if needed it should only be used upon your doctor's recommendation.
General warnings

Drug dependence and abuse

Ultrazac (325/37.5 mg) Tablet has a high potential for addiction and abuse even at recommended dosages, especially with prolonged use. Appropriate monitoring, following safety precautions, is recommended to reduce the risk of drug abuse.

Respiratory disorders

Ultrazac (325/37.5 mg) Tablet should be used with extreme caution in case of respiratory disorders due to the increased risk of worsening of your condition.

Dizziness

Ultrazac (325/37.5 mg) Tablet may cause sleepiness or dizziness. Avoid driving vehicle and operating heavy machinery after taking this medicine.

Suicidal Tendencies

Ultrazac (325/37.5 mg) Tablet should be used with extreme caution in patients exhibiting suicidal tendencies due to the increased risk of worsening of the patient's condition.

Withdrawal symptoms

Abrupt withdrawal of Ultrazac (325/37.5 mg) Tablet may cause withdrawal symptoms. Withdrawal of this medicine should be undertaken gradually using a proper schedule given by your doctor.

Missed Dose

If you have missed Ultrazac (325/37.5 mg) Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take Ultrazac (325/37.5 mg) Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while treatment with Ultrazac (325/37.5 mg) Tablet due to the risk of stomach bleeding, dizziness, fatigue, weakness.
Interaction with Medicine

Amitriptyline

Carbamazepine

Ketoconazole

Phenytoin

Warfarin

Sodium Nitrite

Leflunomide

Prilocaine

Monoamine oxidase inhibitors

Disease interactions

Liver Disease

Patients with liver diseases need special consideration while taking Ultrazac (325/37.5 mg) Tablet. The conversion of this medicine to its active form happens in the liver. Overdose can produce more active forms and leads to liver damage.

Seizures

Maintain caution while using Ultrazac (325/37.5 mg) Tablet in patients with a history of seizures due to the increased risk of recurrent seizures.

Phenylketonuria

Ultrazac (325/37.5 mg) Tablet may contain the artificial sweetener aspartame, which is converted to phenylalanine in the gastrointestinal tract. Hence, this medicine should be used with caution in case there is a history of Phenylketonuria (increased levels of phenylalanine in the blood) where the intake of phenylalanine is restricted.

Intracranial pressure

Ultrazac (325/37.5 mg) Tablet should be used with caution in case of increased intracranial pressure or head injury due to the risk of worsening of your condition.

Acute Alcohol Intoxication

Ultrazac (325/37.5 mg) Tablet is not recommended for use if there is increased alcohol consumption due to the increased risk of adverse effects.
Food interactions
Information not available.
Lab interactions
Information not available.
It is better to take Ultrazac (325/37.5 mg) Tablet with milk or food to prevent an upset stomach. Do not take any other pain killer without asking your doctor first. During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function. Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. It is not recommended to use more than the usual daily dose of this medicine and any other Paracetamol (including over the counter) or Tramadol Hydrochloride containing products concurrently without the advice of your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Ultrazac (325/37.5 mg) Tablet is a combination of Paracetamol and Tramadol. Paracetamol helps in reducing the pain signals responsible for the cause of swelling and pain. Tramadol acts on the brain and nervous system by changing the perception and response to pain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Narcotic analgesic combinations

Schedule

Schedule H

Tramadol hydrochloride/Paracetamol 37.5mg/325mg film-coated tablets - Summary of Product Characteristics (SPC) - (eMC) [Internet]. Medicines.org.uk. 2017 [cited 15 September 2017]. Available from:

http://www.medicines.org.uk/emc/medicine/27233/SPC/Tramadol+hydrochloride+Paracetamol+37.5mg+325mg+film-coated+tablets/

Tramadol/paracetamol fixed-dose combination: a review of its use in the management of moderate to severe pain. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2017 [cited 15 September 2017]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/20701403

Pubchem.ncbi.nlm.nih.gov. 2021. Tramadol. [online] Available at: < [Accessed 26 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/33741>

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>
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Information on this page was last updated on 26 Aug 2021

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