Udenafil

Description

Udenafil relaxes the smooth muscles present in the wall of blood vessels and helps in increasing the flow of blood in certain specific areas of the body. It is used for the treatment of erection dysfunction in adults.

Side effects

Major & minor side effects for Udenafil

  • Headache
  • Heartburn
  • Nausea
  • Diarrhea
  • Flushing
  • Persistent cough
  • Decrease/loss of vision
  • Change in color vision
  • Decrease/loss of hearing
  • Prolonged and painful erection
  • Dizziness
  • Pain in the arms, legs and the back
  • Peeling and blistering of skin
  • Urinary tract infection
  • Nasal congestion
  • Increased sensitivity of the eyes to light

Uses of Udenafil

What is it prescribed for?

  • Erectile Dysfuntion
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 30 to 40 minutes of oral administration. The time may vary from one patient to another.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to udenafil, any other PDE5-inhibitors (sildenafil, tadalafil, vardenafil, etc.), or any other inactive ingredients present in the formulation.

Organic nitrates

This medicine is not recommended for use in patients who are concomitantly taking any medicine that contains organic nitrates such as nitroglycerin, isosorbide, etc. due to the increased risk of worsening of the patient’s condition.

Riociguat

This medicine is not recommended for use in patients who are concomitantly taking a medicine named Riociguat (popular trade name is Adempas) due to the increased risk of worsening of the patient’s condition.

Non-arteritic anterior ischemic optic neuropathy (NAION)

This medicine is not recommended for use in patients with a previous episode of non-arteritic anterior ischemic optic neuropathy due to the increased risk of worsening of the patient’s condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Other medicines

Udenafil may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Hypotension

Use of this medicine may cause a mild and short-lasting decrease in blood pressure. Caution is advised if you are also taking any medication to correct high blood pressure levels since coadministration of these medicines may lower the blood pressure levels too much. Report any unusual symptoms to the doctor on priority. Your doctor will suggest appropriate dose adjustments to avoid or minimize the interaction between the medicines. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Deformation of penis

This medicine should be used with caution in patients having a physical deformity of the penis which may be due to angulation, cavernosal fibrosis, or Peyronie's disease. The risk of permanent loss of sexual potency is significantly high in such cases. An alternative treatment option should be considered based on the clinical condition.

Prolonged and painful erection

This medicine should be used with caution if you have had a painful erection lasting for more than 4 hours in the past due to the increased risk of recurrence. The painful erection may be due to an underlying condition like sickle cell anemia, multiple myeloma, leukemia, etc. Report any unusual symptoms to the doctor on priority. An alternative treatment option may be necessary in some cases based on the clinical condition.

Use in Children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Liver/kidney disease

This medicine should be used with caution in patients having an impairment of normal liver/kidney function. Use of this medicine is not recommended if the impairment is severe. Regular monitoring of liver/kidney function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause symptoms such as blurred vision, dizziness, drowsiness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Nitroglycerin

Amlodipine

Phenytoin

Carbamazepine

Ketoconazole

Cimetidine

Disease interactions

Cardiovascular disorders

Report the incidence of any disease of the heart and blood vessels to the doctor. Use of this medicine is not recommended in such patients, especially the ones who are advised to refrain from any sexual activity, due to the increased risk of severe adverse effects on the heart. An alternative treatment option may be necessary in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with mild to moderate liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition. This medicine is not recommended for use in patients suffering from severe liver diseases.

Priapism

This medicine should be used with caution in patients with priapism, which is characterized by a painful and prolonged erection. This may be caused due to underlying conditions such as sickle cell anemia, leukemia, or deformation of the penis. The risk of permanent tissue damage in the penile area is significantly higher in such cases. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. It is advised to take this medicine at least 30-60 minutes before sexual activity. Report any unusual symptoms to the doctor immediately. Report all your current medicines as well as your medical conditions to the doctor before beginning therapy with this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the smooth muscles present in the walls of blood vessels. This action is limited to particular areas of the body and the flow of blood in these areas are increased.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Impotence agents

Schedule

Schedule H

[Internet]. Jurology.com. 2018 [cited 3 September 2018]. Available from:

https://www.jurology.com/article/S0022-5347(14)01746-7/pdf

Udenafil - DrugBank [Internet]. Drugbank.ca. 2018 [cited 3 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB06267

Kouvelas D e. PDE5 inhibitors: in vitro and in vivo pharmacological profile. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 3 September 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/19860692

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Information on this page was last updated on 11 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.