Loading interface...

Tsart Trio 6.25 Tablet

Manufactured byALKEM LABORATORIES LTD
ContainsChlorthalidone (6.25 mg) + Cilnidipine (10 mg) + Telmisartan (40 mg)
Description
Tsart Trio 6.25 Tablet is a combination medicine that is used for the treatment of high blood pressure (hypertension). Hypertension or high blood pressure is a condition in which the force exerted by the blood against the walls of blood vessels is high. It may also help to reduce the risk of undesirable effects on the heart associated with high blood pressure levels. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect. You can take this medicine with food. You should take this medicine at the same time every day for the ease to remember. Do not stop this medicine on your own even if you feel better as it may worsen the hypertensive condition. The common side effects of Tsart Trio 6.25 Tablet are headache, tiredness and taste change. However, dizziness and ankle swelling may be seen in some patients. If any of these symptoms persist or worsen, consult your doctor at the earliest. Discuss all the known illnesses such as heart disease, kidney disease, liver disease, etc., and about all the active medications with your doctor. Inform the doctor if you are pregnant, planning pregnancy or breastfeeding before taking this medicine. Your doctor may advise you to monitor heart function and blood pressure to assess if this medicine is working properly.

Side effects

Major & minor side effects for Tsart Trio 6.25 Tablet

  • Changes in vision
  • Dizziness
  • Increased heartbeat
  • Difficult or painful urination
  • Diarrhoea
  • Back pain
  • Weakness
  • Muscle pain
  • Fever
  • Shaking of hands or feet
  • Skin Rash
  • Decrease in libido
  • Increased urination frequency
  • Stomach pain
  • Low blood pressure
  • Photosensitivity
  • Constipation
  • Loss of appetite
  • Nausea
  • Vomiting
  • Headache

Uses of Tsart Trio 6.25 Tablet

What is it prescribed for?

  • Hypertension
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time Tsart Trio 6.25 Tablet takes to show its effect is not known.
  • How long do the effects of this medicine last?
    The average time for which Tsart Trio 6.25 Tablet stays in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Tsart Trio 6.25 Tablet due to the increased risk of dizziness, fainting, and very low blood pressure levels. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.
  • Is this a habit forming medicine?
    Tsart Trio 6.25 Tablet has no habit-forming tendencies.
  • Can this medicine be taken during pregnancy?
    is not recommended for use in pregnant women as it may cause oligohydramnios (decreased slight yellowish fluid that surrounds the foetus in the womb), decreases birth weight, prolonged gestation (the time period of birth), etc. Discuss all the potential benefits and risks with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Tsart Trio 6.25 Tablet is known to pass into breastmilk. This medicine may decrease milk production in lactating mothers, low heart rate (bradycardia) in infants and also may dehydrate the infant. It is advisable to discontinue either breastfeeding or this medicine, based on the clinical condition. Discuss all the benefits and risks with your doctor before starting the therapy.

Allergy

Do not take Tsart Trio 6.25 Tablet if you are allergic to chlorthalidone, other sulfonamides, cilnidipine, telmisartan, any other angiotensin-receptor blockers, or any other inactive ingredients present along with these medicines. Seek medical attention if you come across any allergic reactions such as skin rash, hives, swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Aliskiren

Taking Tsart Trio 6.25 Tablet and aliskiren together is not recommended as it may lead to kidney damage, increases blood pressure and hyperkalemia (high potassium levels in the blood). This may cause other undesirable effects such as irregular heartbeat, muscle paralysis, heart attack, etc. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.

Anuria

Taking Tsart Trio 6.25 Tablet in patients suffering from anuria (a condition where the kidney is unable to produce urine) is not recommended as it may cause kidney damage and water retention in the body.

Severe kidney impairment

Tsart Trio 6.25 Tablet is extensively excreted through the kidneys. Taking Tsart Trio 6.25 Tablet in severe kidney impaired patients (Crcl < 30 ml/min) is not recommended as it may accumulate in the kidneys that lead to other undesirable effects and may worsen the compromised kidneys.

Severe liver impairment

Tsart Trio 6.25 Tablet is converted into its active form in the liver. Taking Tsart Trio 6.25 Tablet in severe liver impaired patients is not recommended as it may accumulate in the liver that leads to other undesirable effects and may worsen the compromised liver.
Warnings for special population

Pregnancy

is not recommended for use in pregnant women as it may cause oligohydramnios (decreased slight yellowish fluid that surrounds the foetus in the womb), decreases birth weight, prolonged gestation (the time period of birth), etc. Discuss all the potential benefits and risks with your doctor before taking this medicine.

Breast-feeding

Tsart Trio 6.25 Tablet is known to pass into breastmilk. This medicine may decrease milk production in lactating mothers, low heart rate (bradycardia) in infants and also may dehydrate the infant. It is advisable to discontinue either breastfeeding or this medicine, based on the clinical condition. Discuss all the benefits and risks with your doctor before starting the therapy.
General warnings

Hyperkalemia

Tsart Trio 6.25 Tablet may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Use in children

Tsart Trio 6.25 Tablet is not recommended for use in children since the safety and efficacy of use has not been studied.

Hypotension

Symptomatic hypotension (low blood pressure) may occur in patients with volume depletion or patients who are treated with high-dose diuretics. It is advised to correct this condition before initiating treatment with Tsart Trio 6.25 Tablet.

Volume and electrolyte disturbances

Tsart Trio 6.25 Tablet may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients.

Aortic stenosis

Tsart Trio 6.25 Tablet should be used with extreme caution in patients suffering from aortic stenosis (narrowing or blockage of the aortic valve that regulates blood flow in the chambers of the heart) due to the increased risk of very low blood pressure. Close monitoring of blood pressure is recommended for such patients.

Driving or operating machinery

Use of Tsart Trio 6.25 Tablet may cause symptoms such as drowsiness, blurred vision, or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery during treatment with this medicine if you experience any of these symptoms.

Missed Dose

Take the missed dose of Tsart Trio 6.25 Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume at the scheduled time. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case you suspect Tsart Trio 6.25 Tablet overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Tsart Trio 6.25 Tablet due to the increased risk of dizziness, fainting, and very low blood pressure levels. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.
Interaction with Medicine

Carbamazepine

Cisapride

Lithium

Amiodarone

Insulin

Cimetidine

Ziprasidone

Disease interactions

Congestive heart failure

Congestive heart failure is a condition in which the heart does not pump enough blood to meet the demands of the body. Taking Tsart Trio 6.25 Tablet in this condition may increases the risk of heart attack. Close monitoring of the heart function is indicated.

Cardiogenic shock

Tsart Trio 6.25 Tablet is not recommended for use in patients suffering from a cardiogenic shock (a condition where the heart cannot pump enough blood) due to the increased risk of a heart attack. Close monitoring of heart function is indicated.

Diabetes

Tsart Trio 6.25 Tablet should be used with caution in patients with diabetes mellitus (high blood sugar levels) due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients.

Hyperuricemia

Tsart Trio 6.25 Tablet should be used with caution in patients with hyperuricemia since this medicine decreases the uric acid excretion and increase the risk of acid in the blood which may affect different organs of the body. Close monitoring of the clinical condition is indicated.

Hyperlipidemia

Tsart Trio 6.25 Tablet should be used with caution in patients with hyperlipidemia since it may increase the cholesterol and triglyceride levels. Close monitoring of cholesterol and triglyceride levels is recommended for such patients.
Food interactions
Consumption of grapefruit juice increases the levels of Tsart Trio 6.25 Tablet and is not recommended due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions

Urinary vanillylmandelic acid

Inform the doctor about the use of Tsart Trio 6.25 Tablet if you have been asked to undergo this test for the presence of an adrenal gland tumour. The use of this medicine is likely to give a false value that might be higher than normal.
Take Tsart Trio 6.25 Tablet with or without food. Do not take in larger amounts than prescribed. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Do not self-medicate or stop on your own unless directed by your doctor. Do not crush, break or chew the tablet. Take the tablet immediately after peeling from the strip.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Chlorthalidone works by increasing the excretion of water and sodium from the kidneys. This helps in bringing down the blood pressure as well as reduce swelling (oedema). Cilnidipine and Telmisartan both relax the blood vessels, thus improving blood flow and reducing blood pressure levels. Their combination is thus effective in reducing blood pressure levels.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Thiazide diuretics, Calcium channel blocking agents, Angiotensin receptor blockers, Antihypertensive combinations

Schedule

Schedule H

Go.drugbank.com. 2021. Telmisartan: Uses, Interactions, Mechanism of Action | DrugBank Online. [online] Available at: < [Accessed 14 July 2021].

https://go.drugbank.com/drugs/DB00966>

Go.drugbank.com. 2021. Chlorthalidone: Uses, Interactions, Mechanism of Action | DrugBank Online. [online] Available at: < [Accessed 14 July 2021].

https://go.drugbank.com/drugs/DB00310>

Go.drugbank.com. 2021. Cilnidipine: Uses, Interactions, Mechanism of Action | DrugBank Online. [online] Available at: < [Accessed 15 July 2021].

https://go.drugbank.com/drugs/DB09232>

Drugs, H., 2021. Chlorthalidone: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 15 July 2021].

https://medlineplus.gov/druginfo/meds/a682342.html>

Centaurpharma.com. 2021. [online] Available at: < [Accessed 15 July 2021].

https://www.centaurpharma.com/downloads/CENTAPRES.pdf>

Medicines.org.uk. 2021. Telmisartan 40mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 15 July 2021].

https://www.medicines.org.uk/emc/product/12399/smpc>
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 16 Jul 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.