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Trustiva Tablet
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Trustiva Tablet

Manufactured byHETERO HEALTHCARE LTD
ContainsTenofovir (300 mg) + Emtricitabine (200 mg) + Efavirenz (600 mg)
Description
Trustiva Tablet is an antiviral medicine that consists of Tenofovir, Emtricitabine, and Efavirenz. It is used for the treatment of human immunodeficiency virus (HIV) infection (a condition that occurs when the virus attacks the immune system and interferes with your body's ability to fight infections or diseases). Trustiva Tablet will not cure HIV infection, but it may delay the progression of a chronic, potentially life-threatening condition known as acquired immunodeficiency syndrome (AIDS) and other HIV-related conditions. This medicine works by preventing the virus from multiplying. Trustiva Tablet has some side effects like nausea, vomiting, stomach pain, diarrhoea, headache, confusion, dizziness, trouble sleeping, abnormal dreams, etc. Consult your doctor if they bother you for a long time or become worse. Do not take this medicine if you are allergic to it. Trustiva Tablet is usually taken on an empty stomach, one hour before or two hours after a meal. Take it preferably at bedtime to make some of the side effects less bothersome. Take it in the dose and duration prescribed by your doctor. Do not take more than the recommended dose. Take it every day at the same time to maintain a consistent level of this medicine in your blood. Take this medicine for the recommended duration. Do not discontinue taking this medication without consulting your doctor as it may worsen your condition. Trustiva Tablet may not be suitable for everyone. It is not recommended for use in children weighing less than 40kg. Inform your doctor if you have heart, liver, or kidney problems or any other health conditions. Also, inform your doctor about all your ongoing medications to avoid undesired effects. Trustiva Tablet is unsafe for use during pregnancy. Also, consult your doctor if you planning a pregnancy or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Trustiva Tablet

  • Nausea and Vomiting
  • Diarrhoea
  • Dizziness
  • Headache
  • Abdominal pain
  • Depression
  • Rash
  • Confusion
  • Drowsiness
  • Abnormal dreams
  • Trouble sleeping

Uses of Trustiva Tablet

What is it prescribed for?

  • HIV infection
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for Trustiva Tablet to show its effect is not clinically established.
  • How long do the effects of this medicine last?
    The time duration fwhich Trustiva Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Trustiva Tablet.
  • Can this medicine be taken during pregnancy?
    Trustiva Tablet is unsafe for use during pregnancy as it can harm your developing foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Trustiva Tablet is recommended for use while breastfeeding. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Trustiva Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe liver disease

Trustiva Tablet is not recommended for use if you have severe liver problems, as this medicine may cause liver toxicity and further worsen your condition.

Voriconazole

Voriconazole is an antifungal medicine used to treat fungal infections. Voriconazole may increase the blood concentration of Trustiva Tablet, which may increase the risk of frequent and severe side effects. Hence, combined use of Trustiva Tablet and Voriconazole is not recommended.

Elbasvir/Grazoprevir

Elbasvir/Grazoprevir are antiviral medicines used in the treatment of hepatitis C (a viral infection that causes swelling of the liver). Trustiva Tablet may decrease the blood concentration of Elbasvir/Grazoprevir, resulting in the loss of its therapeutic effect. Hence, the combined use of Trustiva Tablet and Elbasvir/Grazoprevir is not recommended.
Warnings for special population

Pregnancy

Trustiva Tablet is unsafe for use during pregnancy as it can harm your developing foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

Trustiva Tablet is recommended for use while breastfeeding. Hence, consult your doctor if you are breastfeeding.
General warnings

Immune reconstitution syndrome

Changes in your immune system can occur when you start taking Trustiva Tablet. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. It may cause an exaggerated response making the symptoms of infection worse. Inform your doctor if you develop any new symptoms after starting treatment with Trustiva Tablet.

Fat redistribution

Trustiva Tablet should be used with caution as it may cause redistribution or accumulation of body fat. It may result in central obesity, buffalo hump (excess fat behind the neck), peripheral wasting (difficulty in moving an arm or leg or making any movement), facial wasting (fat loss in the cheeks and temples), breast enlargement, and cushingoid appearance (extra fat build up on the sides of the face and weight gain). Consult your doctor if you have any concerns.

Lactic acidosis

Lactic acidosis is a build-up of lactic acid in the bloodstream. Trustiva Tablet should be used with caution due to the increased risk of lactic acidosis. Report any unusual symptoms like muscle cramps, unusual weakness or tiredness, feeling dizzy or lightheaded, fast or abnormal heartbeat, etc., to your doctor immediately.

Decreased bone mineral density

Trustiva Tablet should be used with caution as it may cause a decrease in bone mineral density (amount of bone mineral in your bones).

Driving or operating machines

Trustiva Tablet may cause dizziness, drowsiness, and impaired concentration. Hence, avoid performing activities that require mental alertness such as driving vehicles or operating machines if you experience such symptoms.

Missed Dose

Take the missed dose of Trustiva Tablet as soon as you remember. Skip the missed dose if it is time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Never take more than the prescribed dose of Trustiva Tablet. Seek emergency medical treatment in case of an overdose for further guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Citalopram

Fluconazole

Amiodarone

Ciprofloxacin

Azithromycin

Disease interactions

Increase in cholesterol levels

Trustiva Tablet should be used with caution as it may cause an increase in cholesterol and triglycerides (a type of fat) levels in the body. Your doctor may suggest blood tests for periodic monitoring of your cholesterol and triglycerides levels while you are taking this medicine.

CNS disorders

Use of Trustiva Tablet may cause depression, aggressive behaviour, confusion, suicidal thoughts, etc. Hence this medicine should be used with extreme caution if you have a history of mental problems due to the increased risk of worsening your condition. Inform your doctor if you notice any change in mood and behaviour or develop thoughts of self-harm.

Kidney Disease

Trustiva Tablet should be used with caution if you have kidney problems as this medicine may further worsen your condition. Your doctor may adjust the dose based on your clinical condition.

QT Prolongation

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Trustiva Tablet should be used with caution as it may cause QT prolongation. It is not recommended for use if you have any clinical condition or taking any medication known to cause QT prolongation.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Trustiva Tablet as instructed by your doctor. Do not take in larger or smaller quantities than recommended. Avoid the discontinuation of this medicine without consulting your doctor, as it can worsen your condition. Inform your doctor immediately if you experience any change in mood or behaviour or develop suicidal thoughts. Your doctor may suggest tests to monitor your liver function and lipid (fats) levels during treatment with this medicine. Avoid driving vehicles or operating machines, as this medicine can make you feel dizzy or drowsy. This medicine may cause redistribution and accumulation of body fat in different parts of your body, such as below your neck, upper back, breasts, or around the stomach. It may also cause loss of body fat from your legs, arms, and face. Consult your doctor if you have any concerns.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Causes sleepiness

How it works
Trustiva Tablet works by stopping the human immunodeficiency virus (HIV) from multiplying.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Antiviral combinations

Schedule

Schedule H

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CiplaMed. 2022. VIRADAY Tablets. [online] Available at: < [Accessed 1 February 2022].

https://ciplamed.com/content/viraday-tablets>

Drugs, H., 2021. Efavirenz: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 23 November 2021].

https://medlineplus.gov/druginfo/meds/a699004.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - SUSTIVA- efavirenz capsule, gelatin coatedSUSTIVA- efavirenz capsule, gelatin coatedSUSTIVA- efavirenz tablet, film coated. [online] Available at: < [Accessed 23 November 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=32d6371e-ba56-4294-b732-6d43627c5c47>
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Information on this page was last updated on 14 Feb 2022

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