Trospium

Description

Trospium is used for the treatment of an overactive bladder, a condition characterized by symptoms such as a frequent feeling of a need to urinate, sudden urge to urinate, inability to control urination, leaking of urine, etc. This medicine is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Trospium

  • Dry mouth
  • Constipation
  • Headache
  • Nausea and vomiting
  • Dizziness
  • Weakness
  • Dry eyes
  • Nasal dryness
  • Back pain
  • Skin rash

Uses of Trospium

What is it prescribed for?

  • Overactive Bladder
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is recommended.

Allergy

This medicine is not recommended for use in patients with a known allergy to trospium or any other inactive ingredients present along with it.

Urinary retention

This medicine is not recommended for use in patients suffering from urinary retention, a condition where the patient is unable to empty the bladder, due to the increased risk of worsening of the patient's condition.

Narrow angle glaucoma

This medicine is not recommended for use in patients suffering from an uncontrolled narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Gastric retention

This medicine is not recommended for use in patients suffering from gastric retention due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is recommended.
General warnings

Angioedema and anaphylactic reactions

Use of this medicine may cause angioedema (swelling) of the face, lips, tongue, etc. as well as severe allergic reactions in some patients. Seek immediate medical intervention if any such reactions develop. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Central nervous system side effects

Use of this medicine may cause central nervous system side effects such as a headache, confusion, hallucinations, sleepiness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any such symptoms during treatment with this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Use in Children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machinery

Use of this medicine may cause symptoms such as dizziness, drowsiness, blurred vision, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Liver Disease

This medicine should be used with caution in patients suffering from moderate or severe liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Olanzapine

Topiramate

Ketoconazole

Zonisamide

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine relaxes the urinary bladder muscles; this helps the bladder to retain a larger amount of urine and prevents the symptoms of an overactive bladder.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Urinary antispasmodics

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 7 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021595s006lbl.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 7 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022103s004lbl.pdf

DailyMed - trospium chloride capsule, extended release [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 7 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8b8d434c-daa2-4bf2-bde6-3e59f81bd88b

DailyMed - trospium chloride tablet [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 7 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cd0d2e18-9e16-ac18-c35c-a150bb5cb67b

Regurin 20mg tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 7 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/6643/smpc

Trospium - DrugBank [Internet]. Drugbank.ca. 2018 [cited 7 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00209

Trospium: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 7 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a604037.html

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Information on this page was last updated on 12 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.