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Troid 0.2 % Lotion

Manufactured by: Resilient Cosmeceuticals Pvt. Ltd.
Composition: Trioxsalen
Prescription Required: Yes
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Description

Troid 0.2 % Lotion is used along with an ultraviolet light in the treatment called psoralen plus ultraviolet light A (PUVA) to treat vitiligo, a condition characterized by loss of skin color. This medicine is also used to increase the tolerance of skin to sunlight.

Side effects

Major & minor side effects for Troid 0.2 % Lotion

  • Blistering and peeling of skinsevere
  • Reddened and sore skinsevere
  • Swelling of feet or lower legssevere
  • Itching of skinsevere
  • Nauseasevere
  • Dizziness
  • Mental depression
  • Nervousness
  • Trouble sleeping
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Troid 0.2 % Lotion

Onset of action

The time required for this medicine to show its action is about 6 months for vitiligo and about 1 hour for increasing the sensitivity of the skin to sunlight.

Duration of effect

The time until which this medicine remains active in the body is about 8 hours when it is used to increase the sensitivity of skin to sunlight.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is not recommended for use in pregnant women since the safety and efficacy of use are not established.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not established.

What is it prescribed for?

Uses of Troid 0.2 % Lotion

  • Vitiligo

    This medicine is used in the treatment of Vitiligo, a condition characterized by loss of skin color.
  • Increasing tolerance to sunlight

    Troid 0.2 % Lotion is used to increase the tolerance of skin to sunlight or ultraviolet light.

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When not to use?

Contraindications of Troid 0.2 % Lotion

  • Porphyria

    This medicine is not recommended for use in patients with a known history of porphyria due to the increased risk of worsening of the patient's condition.
  • Acute autoimmune disease

    This medicine is not recommended for use in patients with an autoimmune disorder due to the increased risk of severe adverse effects.
  • Allergy

    This medicine is not recommended for use in patients with a known allergy to trioxsalen or any other inactive ingredients present along with it.

Dosage

  • Missed Dose

    Inform the doctor immediately if you miss taking/applying a dose of Troid 0.2 % Lotion. Your doctor will instruct you on the further dosing schedule.
  • Overdose

    Seek emergency medical treatment or contact the doctor immediately in case an overdose of this medicine is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Tetracyclinessevere
  • Phenothiazinesmoderate

Disease interactions

  • Hepatic impairment

    moderate
    Troid 0.2 % Lotion should be used with caution in patients with a history of liver diseases and active liver diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments, frequent liver function monitoring, or replacement with a suitable alternative may be required based on the clinical condition.
  • Heart Disease

    minor
    Troid 0.2 % Lotion should be used with caution in patients with a history of heart diseases and active heart diseases due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine in such patients. Replacement with a suitable alternative may be required based on the clinical condition.

Food interactions

  • It is advised to avoid eating limes, figs, parsley, mustard, carrots, celery, etc. while using this medicine due to the risk of serious adverse effects such as bad burns or blisters. Your doctor/dietitian may suggest appropriate changes in your diet to avoid this interaction.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Tablets: Troid 0.2 % Lotion may be taken with meals or milk. Do not take in larger or smaller amounts that advised/prescribed. Lotion: Apply Troid 0.2 % Lotion exactly as advised by the doctor. Do not apply in larger or smaller amounts than prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use in pregnant women since the safety and efficacy of use are not established.
  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not established.

General warnings

  • Allergy to sunlight

    - This medicine should be used with extreme caution in patients with a known allergy to sunlight due to the increased risk of severe adverse effects. Any unusual symptoms should be reported to the doctor on priority. Discontinuation of therapy may be required based on the clinical condition.
  • Eye problems

    - This medicine should be used with extreme caution in patients with a known history of eye problems due to the increased risk of worsening of the patient's condition. Close monitoring of vision is recommended for such patients. Discontinuation of therapy may be required based on the clinical condition.
  • Gastrointestinal diseases

    - This medicine should be used with extreme caution in patients with a history of gastrointestinal diseases due to the increased risk of worsening of the patient's condition. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments or discontinuation of therapy may be required based on the clinical condition.
  • Melanoma or other skin cancer

    - This medicine should be used with extreme caution in patients with a known history of melanoma or other skin cancer due to the increased risk of recurrent skin cancer. Any unusual symptoms should be reported to the doctor on priority. Discontinuation of therapy may be required based on the clinical condition.
  • Renal impairment

    - This medicine should be used with extreme caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Any unusual symptoms should be reported to the doctor on priority. It is recommended to perform kidney function tests before beginning treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Other details

  • To be taken with food
  • To be taken as instructed by doctor
  • Does not cause sleepiness

How it works

It works by increasing the sensitivity of the skin to sunlight or ultraviolet light.

Legal Status

Approved
Unknown
Unknown
Unknown

Classification

Category
Psoralens
Schedule
N/A

References

  • Human Metabolome Database: Showing metabocard for Trioxsalen (HMDB0015575) [Internet]. Hmdb.ca. 2017 [cited 11 September 2017]. Available from: http://www.hmdb.ca/metabolites/HMDB15575
  • Trioxsalen [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 11 September 2017]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/5585
  • Katare O, Garg B, Saraswat A, Bhatia A. Topical treatment in vitiligo and the potential uses of new drug delivery systems. Indian Journal of Dermatology, Venereology, and Leprology. 2010;76(3):231.
  • Sehgal V. Effectiveness of Trioxsalen Therapy for Vitiligo. Archives of Dermatology. 1974;110(6):957.
  • Trioxsalen - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 September 2017]. Available from: https://www.drugbank.ca/drugs/DB04571

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Information on this page was last updated on 14 Sep 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.